TRAPPC12 and TRAPPC9

Data Source:
BioGRID (two hybrid)

		TRAPPC12	TRAPPC9
Description		trafficking protein particle complex subunit 12	trafficking protein particle complex subunit 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol TRAPP Complex Perinuclear Region Of Cytoplasm	Golgi Membrane Endoplasmic Reticulum Trans-Golgi Network Cytosol TRAPP Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Proteolysis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Metaphase Plate Congression Regulation Of Kinetochore Assembly Positive Regulation Of Protein Localization To Kinetochore	Cerebral Cortex Development Neuron Differentiation COPII Vesicle Coating Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		RAB GEFs exchange GTP for GDP on RABs	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases			Nonsyndromic autosomal recessive mental retardation (NS-ARMR)
GWAS		Neuritic plaques or neurofibrillary tangles or cerebral amyloid angiopathy (pleiotropy) ( 29458411) Serum immune biomarker levels ( 32066700)	Blood pressure (smoking interaction) ( 25189868) Diastolic blood pressure ( 30578418) Disease progression in age-related macular degeneration ( 29346644) Emphysema distribution in smoking ( 27669027) Hip circumference adjusted for BMI ( 28552196) Major depressive disorder ( 29317602) Obesity-related traits ( 23251661) Pars opercularis volume ( 31530798) Pediatric non-alcoholic fatty liver disease activity score ( 28918882) Pulse pressure ( 28135244 27841878 28739976 30578418) Response to (pegylated) interferon in chronic hepatitis B ( 30715261) Response to amphetamines ( 22952603) Systolic blood pressure ( 27841878)
Interacting Genes		13 interacting genes: ARNTL FBXO7 HNRNPA2B1 LIN7B MTDH RSKR TFCP2 TRAPPC10 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9	5 interacting genes: APP TRAPPC12 TRAPPC2 TRAPPC3L TRAPPC8
Entrez ID		51112	83696
HPRD ID		15580	18136
Ensembl ID		ENSG00000171853	ENSG00000167632
Uniprot IDs		A0A0J9YXQ9 Q8WVT3	Q96Q05
PDB IDs
Enriched GO Terms of Interacting Partners?
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