TNNI3K and FABP3

Data Source:
HPRD (two hybrid)

		TNNI3K	FABP3
Description		TNNI3 interacting kinase	fatty acid binding protein 3
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Space Cytosol Sarcoplasm Extracellular Exosome
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Protein C-terminus Binding Troponin I Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Long-chain Fatty Acid Transporter Activity Protein Binding Cytoskeletal Protein Binding Long-chain Fatty Acid Binding Icosatetraenoic Acid Binding Oleic Acid Binding
	Biological Process	Regulation Of Heart Rate Protein Phosphorylation Regulation Of Cardiac Muscle Contraction Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Cardiac Conduction	Fatty Acid Metabolic Process Negative Regulation Of Cell Population Proliferation Long-chain Fatty Acid Transport Triglyceride Catabolic Process Intracellular Lipid Transport Response To Insulin Response To Drug Cholesterol Homeostasis Regulation Of Fatty Acid Oxidation Brown Fat Cell Differentiation Phospholipid Homeostasis Response To Fatty Acid Positive Regulation Of Phospholipid Biosynthetic Process Positive Regulation Of Long-chain Fatty Acid Import Into Cell Regulation Of Phosphatidylcholine Biosynthetic Process
Pathways			Triglyceride catabolism
Drugs		Fostamatinib
Diseases
GWAS		Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 26426971 23669352 28892062 20935630 28448500) Body mass index (age <50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Body size at age 10 ( 32376654) Childhood body mass index ( 33045005 26604143) Hip circumference ( 25673412) Menarche (age at onset) ( 27182965 25231870) Mental health study participation (completed survey) ( 31263887) Obesity ( 23563607) Parental longevity (combined parental age at death) ( 29227965) Pubertal anthropometrics ( 23449627) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032)	Alcohol dependence ( 23455491) Body mass index ( 26426971) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
Interacting Genes		8 interacting genes: ACTA1 ACTC1 AIP FABP3 FBXO4 HADHB MYBPC3 TNNI3	4 interacting genes: NUP62 SHTN1 TNNI3K VPS28
Entrez ID		51086	2170
HPRD ID		18208	00613
Ensembl ID		ENSG00000116783	ENSG00000121769
Uniprot IDs		Q59H18	A0A384MDY5 P05413
PDB IDs		4YFF 4YFI 6B5J	1G5W 1HMR 1HMS 1HMT 2HMB 3RSW 3WBG 3WVM 3WXQ 4TJZ 4TKB 4TKH 4TKJ 4WBK 5B27 5B28 5B29 5CE4 5HZ9 6AQ1
Enriched GO Terms of Interacting Partners?
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