TXNDC12 and DPF2

Data Source:
BioGRID (two hybrid)

		TXNDC12	DPF2
Description		thioredoxin domain containing 12	double PHD fingers 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Chromatin Nucleus Nucleoplasm Centrosome Cytosol Intracellular Membrane-bounded Organelle NBAF Complex
	Molecular Function	Protein Binding Peptide Disulfide Oxidoreductase Activity Protein-disulfide Reductase (glutathione) Activity	Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Histone Binding Metal Ion Binding H3K9me3 Modified Histone Binding Lysine-acetylated Histone Binding
	Biological Process	Negative Regulation Of Cell Death Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Apoptotic Process Nervous System Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Apoptotic Signaling Pathway Negative Regulation Of Myeloid Progenitor Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Mean spheric corpuscular volume ( 32888494) Urate levels ( 31578528)
Interacting Genes		9 interacting genes: CAMLG DPF2 FKBP7 KLHL2 SGTA SGTB UBQLN1 UBQLN2 ZDHHC17	20 interacting genes: FHL2 GOLGA6L9 H3-4 H3C1 H4C1 HSF2BP LDOC1 LNX1 MEOX2 NFKB2 PICK1 REL RELB RINT1 RUBCN TTC23L TXNDC12 UPF2 ZNF212 ZNF655
Entrez ID		51060	5977
HPRD ID		11633	03394
Ensembl ID		ENSG00000117862	ENSG00000133884
Uniprot IDs		O95881	A0A024R582 J3KMZ8 Q92785
PDB IDs		1SEN 2K8V	3IUF 5B79 5VDC 6LTH 6LTJ
Enriched GO Terms of Interacting Partners?
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