RHBDD2 and CIAO2A

Data Source:
BioGRID (two hybrid)

		RHBDD2	CIAO2A
Description		rhomboid domain containing 2	cytosolic iron-sulfur assembly component 2A
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Hrd1p Ubiquitin Ligase ERAD-L Complex Nucleoplasm Golgi Apparatus Integral Component Of Endoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Nucleoplasm Cytosol CIA Complex
	Molecular Function	Serine-type Endopeptidase Activity Misfolded Protein Binding Ubiquitin-specific Protease Binding	Protein Binding Metal Ion Binding
	Biological Process	Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response	Chromosome Segregation Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer Protein Maturation By [4Fe-4S] Cluster Transfer
Pathways
Drugs
Diseases
GWAS		Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		58 interacting genes: ABHD16A ACSF2 ADORA2A BCL2L1 BCL2L2 CCR9 CHRM4 CIAO2A CIDEB COL8A1 COMT DIABLO DRD2 DYNC1H1 ERBB2 FKBP8 FMO4 GAL3ST3 GCSH GDF5-AS1 H2BC3 H4C7 IFI27L1 IL32 LETMD1 LIG4 MAOB MFSD14C MICOS13 MIEF2 MLX MMRN2 MPC2 MRM1 MRPL35 MTERF3 MYG1 NAALAD2 NCBP2AS2 NFU1 NRM PBX3 PTAFR ROMO1 RSAD2 SCGB3A1 SDHD SLC25A2 SLC25A3 SNPH SYT16 TEX44 THBD TIMM17B TPRG1 TSR1 TUFM USP30	25 interacting genes: AGTRAP APOA2 CIAO1 CMTM6 CREB3L1 DERL1 DGAT2L6 EBAG9 ERGIC3 FKBP7 GJA8 GSC2 KCNIP1 LIME1 MEST PLP2 PLPP6 PLPPR2 PRAF2 RHBDD2 SETD4 SIN3A TMED8 TNFRSF10D VAMP3
Entrez ID		57414	84191
HPRD ID		11492	08010
Ensembl ID		ENSG00000005486	ENSG00000166797
Uniprot IDs		Q6NTF9	Q9H5X1
PDB IDs			2M5H 3UX2 3UX3
Enriched GO Terms of Interacting Partners?
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