PCCB and PCCA

Data Source:
HPRD (two hybrid)

		PCCB	PCCA
Description		propionyl-CoA carboxylase subunit beta	propionyl-CoA carboxylase subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol	Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Propionyl-CoA Carboxylase Activity Protein Binding ATP Binding	Propionyl-CoA Carboxylase Activity Protein Binding ATP Binding Biotin Binding CoA Carboxylase Activity Enzyme Binding Metal Ion Binding
	Biological Process	Biotin Metabolic Process Short-chain Fatty Acid Catabolic Process	Biotin Metabolic Process Short-chain Fatty Acid Catabolic Process
Pathways		Biotin transport and metabolism Defective HLCS causes multiple carboxylase deficiency Propionyl-CoA catabolism	Biotin transport and metabolism Defective HLCS causes multiple carboxylase deficiency Propionyl-CoA catabolism
Drugs		Biotin Valine	Biotin
Diseases		Propionic acidemia	Propionic acidemia
GWAS		Alanine transaminase levels ( 29403010) Autism spectrum disorder or schizophrenia ( 28540026) Coronary artery disease ( 33020668) Fibrinogen ( 20031576 23969696) Fibrinogen levels ( 28107422) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Height ( 28552196 20881960) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Metabolic syndrome ( 31589552) Non-word reading ( 30741946) Schizophrenia ( 28991256 25056061 29483656) Systolic blood pressure ( 30224653) Total bilirubin levels ( 29403010) Triglyceride levels ( 32203549 32154731) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)	Chromosomal aberration frequency (chromatid type) in genotoxic compound exposure ( 31586183) Corpus callosum anterior volume ( 31530798) Metabolite levels ( 23823483) Myopia ( 27182965) Refractive error ( 23396134 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation (ever regular vs never regular) ( 30679032) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		5 interacting genes: ACTN3 FBXL17 MTDH PCAT1 PCCA	4 interacting genes: ERRFI1 MCC PCCB PJA1
Entrez ID		5096	5095
HPRD ID		01982	01981
Ensembl ID		ENSG00000114054	ENSG00000175198
Uniprot IDs		P05166	P05165
PDB IDs			2CQY 2JKU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?