SHANK1 and DLGAP1

  • Data Source:
  • BioGRID (x-ray crystallography)
  • HPRD (in vivo, in vitro)

SHANK1

DLGAP1

Description SH3 and multiple ankyrin repeat domains 1 DLG associated protein 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase levels ( 31219225)
  • Body fat mass ( 28552196)
  • Cardiac Troponin-T levels ( 23247143)
  • Eating disorders ( 22911880)
  • Economic and political preferences (time) ( 22566634)
  • Erythrocyte cadmium concentration in never smokers ( 27005419)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Hip circumference adjusted for BMI ( 28552196)
  • Initial alcohol sensitivity ( 30276832)
  • Mean corpuscular volume ( 32888494)
  • Mean reticulocyte volume ( 32888494)
  • Mean spheric corpuscular volume ( 32888494)
  • Menarche (age at onset) ( 27182965 25231870)
  • Midgestational circulating levels of PBDEs ( 28235828)
  • Obesity-related traits ( 23251661)
  • Plasma free amino acid levels ( 30659259)
  • Response to fenofibrate (total cholesterol levels) ( 27002377)
  • Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485)
  • Trunk fat mass ( 28552196)
  • Upper eyelid sagging severity ( 24869959)
Interacting Genes 19 interacting genes: ABCA1 ACE2 ADGRB2 ADGRL1 ADGRL2 ARHGEF7 BAIAP2 DLG4 DLGAP1 DNM2 HOMER1 RPS6KA2 RPS6KA3 SHARPIN SPTAN1 SSTR2 STAT1 TANC1 USP8 24 interacting genes: APC DLG1 DLG2 DLG3 DLG4 DLGAP2 DLGAP3 DYNLL1 DYNLL2 FHL2 GRB2 GRIN2A GRIN2C ITSN1 ITSN2 KCNA4 MAGEA11 MAGI2 MYO5A SHANK1 SHANK2 SHANK3 SORBS2 TANC1
Entrez ID 50944 9229
HPRD ID 05413 09260
Ensembl ID ENSG00000161681 ENSG00000170579
Uniprot IDs H9KV90 Q9Y566 A0A0A0MTP4 A8MXQ8 B7Z2J5 O14490 Q6IS01
PDB IDs 6CPI 5YPO
Enriched GO Terms of Interacting Partners?
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