CDON and NRGN

Data Source:
BioGRID (affinity chromatography technology)

		CDON	NRGN
Description		cell adhesion associated, oncogene regulated	neurogranin
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Collagen-containing Extracellular Matrix	Nucleus Cytosol Trans-Golgi Network Transport Vesicle Membrane Postsynaptic Density Axon Mitochondrial Membrane Neuronal Cell Body Dendritic Spine Head Postsynaptic Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding	Calmodulin Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidic Acid Binding
	Biological Process	Cell Fate Specification Positive Regulation Of Protein Phosphorylation Lens Development In Camera-type Eye Cell Adhesion Smoothened Signaling Pathway Myoblast Fusion Anterior/posterior Pattern Specification Embryonic Body Morphogenesis Skeletal Muscle Satellite Cell Differentiation Cerebral Cortex Development Regulation Of Protein Binding Positive Regulation Of MAPK Cascade Positive Regulation Of Myoblast Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Muscle Cell Differentiation Embryonic Retina Morphogenesis In Camera-type Eye Positive Regulation Of Neural Precursor Cell Proliferation	Signal Transduction Nervous System Development Associative Learning Telencephalon Development Postsynaptic Modulation Of Chemical Synaptic Transmission Positive Regulation Of Long-term Synaptic Potentiation
Pathways		Myogenesis Myogenesis Ligand-receptor interactions Activation of SMO	Long-term potentiation Long-term potentiation
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 22881374) Blood protein levels ( 30072576 29875488 28240269) Cerebral white matter volume ( 31530798) Height ( 31562340) Lung function (FEV1) ( 28166213) Mild to moderate chronic kidney disease ( 31178898) Primary tooth development (time to first tooth eruption) ( 23704328) Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 28991256 25056061 19571808 29483656 30285260)
Interacting Genes		5 interacting genes: ABL1 BOC CDH15 CDH2 CTNNB1	6 interacting genes: CALM1 EIF5 GLP1R PRKCA PRKCB PRKCG
Entrez ID		50937	4900
HPRD ID		16372	03828
Ensembl ID		ENSG00000064309	ENSG00000154146
Uniprot IDs		Q4KMG0	A0A024R3M7 Q92686
PDB IDs		3D1M 3N1F 3N1Q
Enriched GO Terms of Interacting Partners?
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