CDON and CDH15

Data Source:
HPRD (in vivo)

		CDON	CDH15
Description		cell adhesion associated, oncogene regulated	cadherin 15
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Collagen-containing Extracellular Matrix	Golgi Apparatus Plasma Membrane Caveola Integral Component Of Membrane Catenin Complex Neuromuscular Junction Extracellular Exosome
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Cadherin Binding
	Biological Process	Cell Fate Specification Positive Regulation Of Protein Phosphorylation Lens Development In Camera-type Eye Cell Adhesion Smoothened Signaling Pathway Myoblast Fusion Anterior/posterior Pattern Specification Embryonic Body Morphogenesis Skeletal Muscle Satellite Cell Differentiation Cerebral Cortex Development Regulation Of Protein Binding Positive Regulation Of MAPK Cascade Positive Regulation Of Myoblast Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Muscle Cell Differentiation Embryonic Retina Morphogenesis In Camera-type Eye Positive Regulation Of Neural Precursor Cell Proliferation	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Adherens Junction Organization Positive Regulation Of Muscle Cell Differentiation Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Pathways		Myogenesis Myogenesis Ligand-receptor interactions Activation of SMO	Adherens junctions interactions Myogenesis Myogenesis
Drugs
Diseases			Non-syndromic autosomal dominant mental retardation
GWAS		Alzheimer's disease (late onset) ( 22881374) Blood protein levels ( 30072576 29875488 28240269) Cerebral white matter volume ( 31530798) Height ( 31562340) Lung function (FEV1) ( 28166213) Mild to moderate chronic kidney disease ( 31178898) Primary tooth development (time to first tooth eruption) ( 23704328) Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		5 interacting genes: ABL1 BOC CDH15 CDH2 CTNNB1	12 interacting genes: ARVCF BOC CDH7 CDH9 CDON CTNNA1 CTNNB1 GNA12 JUP SGTA SGTB UBQLN2
Entrez ID		50937	1013
HPRD ID		16372	00225
Ensembl ID		ENSG00000064309	ENSG00000129910
Uniprot IDs		Q4KMG0	P55291
PDB IDs		3D1M 3N1F 3N1Q
Enriched GO Terms of Interacting Partners?
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