PAX9 and ZNF580

Data Source:
BioGRID (two hybrid)

		PAX9	ZNF580
Description		paired box 9	zinc finger protein 580
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Endoderm Development Odontogenesis Regulation Of Odontogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development Face Morphogenesis Cellular Response To Growth Factor Stimulus	Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Leukocyte Chemotaxis Regulation Of Transcription By RNA Polymerase II Chemotaxis Inflammatory Response Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Gene Expression Positive Regulation Of Interleukin-8 Production Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Hydrogen Peroxide
Pathways
Drugs
Diseases		Tooth agenesis; Hypodontia
GWAS		Breast cancer ( 29059683 23535729) Height ( 28552196) Lobe attachment (rater scored) ( 29198719) Lobe attachment (rater-scored or self-reported) ( 29198719) Nonsyndromic cleft palate ( 31609978) Prostate cancer ( 29892016)
Interacting Genes		26 interacting genes: EYA2 FUBP3 GTF2A1L KDM5B KLF4 KRTAP13-3 LMO2 MSX1 MYLIP NR0B2 PFDN5 PLAGL2 SFN SLAIN1 SSX4 TEPSIN TLE1 TLE2 TLE5 TRIP13 TRIP4 VPS37C WWOX ZNF343 ZNF440 ZNF580	27 interacting genes: ARHGEF6 BANP CCDC136 CYSRT1 FSD2 GOLGA6L9 HOMEZ IKZF1 KHDRBS3 KRT27 KRT34 KRT40 KRTAP10-7 KRTAP10-8 MDFI MTUS2 NBPF19 NOTCH2NLA PAX9 PSTPIP1 RAD54B SH3GL2 TRIM27 TRIP6 TSC22D4 XBP1 ZNF436
Entrez ID		5083	51157
HPRD ID		01336	18353
Ensembl ID		ENSG00000198807	ENSG00000213015
Uniprot IDs		P55771 Q2L4T1	Q9UK33
PDB IDs
Enriched GO Terms of Interacting Partners?
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