GEMIN4 and HR

Data Source:
BioGRID (two hybrid)

		GEMIN4	HR
Description		gem nuclear organelle associated protein 4	HR lysine demethylase and nuclear receptor corepressor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cytosol Cajal Body Membrane Nuclear Body Small Nuclear Ribonucleoprotein Complex SMN Complex SMN-Sm Protein Complex Extracellular Exosome Gemini Of Coiled Bodies	Histone Deacetylase Complex Chromatin Nucleoplasm
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding	Transcription Coregulator Activity Protein Binding Oxidoreductase Activity Chromatin DNA Binding Histone Demethylase Activity (H3-K9 Specific) Metal Ion Binding
	Biological Process	Spliceosomal SnRNP Assembly RRNA Processing Import Into Nucleus	Regulation Of Transcription By RNA Polymerase II Histone H3-K9 Demethylation
Pathways		snRNP Assembly
Drugs
Diseases			Atrichia with papular lesions Localized autosomal recessive hypotrichosis Marie-Unna hereditary hypotrichosis (MUHH)
GWAS		Prostate cancer ( 23535732)	Obesity-related traits ( 23251661)
Interacting Genes		55 interacting genes: AGO2 ALPP CALCOCO2 CCDC185 CCT3 CDC20B CERCAM CFP DDX20 DHX9 DMPK FBXL12 FLAD1 GEMIN5 GLYR1 HR KANK2 KARS1 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP2-3 KRTAP2-4 KRTAP9-2 LGALS1 LGALS3 LY86 MORC4 NPPB NUFIP1 PIAS3 PSMB1 PTCD1 PTEN RAD51D RN7SL1 RNU1-1 RNU2-1 S1PR4 SNRPB SNRPD1 SNRPD2 SPG21 SPRY1 SQSTM1 SRRT STXBP2 STXBP3 TAP1 TOP1 UFC1 USP15 USP2 ZNF326 ZNF35	35 interacting genes: AMMECR1 ATP23 C11orf1 C19orf54 CNFN CYSRT1 FAM168A GEMIN4 HDAC1 HDAC3 HDAC5 HMGB1 HOXA1 INCA1 KLHL20 KRTAP11-1 KRTAP13-2 KRTAP15-1 KRTAP3-1 KRTAP3-3 KRTAP6-3 MGAT5B PLA2G10 PRKCA RARA RARB RBP3 SPAG8 SPRY3 TBL1X TRIM27 TSC1 VDR YPEL3 ZMYND12
Entrez ID		50628	55806
HPRD ID		07370	03808
Ensembl ID		ENSG00000179409	ENSG00000168453
Uniprot IDs		I3L2C7 P57678 Q8WUM5	O43593
PDB IDs
Enriched GO Terms of Interacting Partners?
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