ATP5F1B and RPP14

Data Source:
BioGRID (two hybrid)

		ATP5F1B	RPP14
Description		ATP synthase F1 subunit beta	ribonuclease P/MRP subunit p14
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Proton-transporting ATP Synthase, Catalytic Core Mitochondrial Matrix Plasma Membrane Cell Surface Membrane Mitochondrial Membrane Mitochondrial Nucleoid Proton-transporting ATP Synthase Complex Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Extracellular Exosome	Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex
	Molecular Function	Protein Binding ATP Binding ATPase Activity MHC Class I Protein Binding Angiostatin Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	Angiogenesis Osteoblast Differentiation Generation Of Precursor Metabolites And Energy Lipid Metabolic Process ATP Biosynthetic Process Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Mitochondrion Organization Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Intracellular PH Cellular Response To Interleukin-7 Proton Transmembrane Transport	TRNA 5'-leader Removal RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		Mitochondrial protein import Mitochondrial protein import Formation of ATP by chemiosmotic coupling Transcriptional activation of mitochondrial biogenesis Cristae formation	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs		Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE Phenethyl Isothiocyanate
Diseases
GWAS			Height ( 28552196) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494) Refractive error ( 32231278) Rheumatoid arthritis (ACPA-positive) ( 24532676) Total cholesterol levels ( 30275531)
Interacting Genes		24 interacting genes: ANXA7 APOA1 ATP5F1C ATP5PF ATPAF1 ATPAF2 BYSL CDK4 CDKN1A FANCA GRB7 HMOX2 LNX2 PIN1 PLG PSME3 RPP14 SMN1 SUMO4 TERT TK1 TRIM55 TRIM63 YWHAG	22 interacting genes: A2M ACTN2 ATP5F1B CAPZB DOCK7 EXOSC8 GEMIN2 IGSF21 KMT2B LIMD1 MSH2 NOVA1 PKM POP4 POP5 PSME1 RPP25 RPP30 RPP38 RPP40 WIZ ZNF277
Entrez ID		506	11102
HPRD ID		00044	18001
Ensembl ID		ENSG00000110955	ENSG00000163684
Uniprot IDs		P06576 V9HW31	O95059
PDB IDs			6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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