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OTX2 and HOMER3
Data Source:
BioGRID
(two hybrid)
OTX2
HOMER3
Description
orthodenticle homeobox 2
homer scaffold protein 3
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Growth Cone
Protein-containing Complex
Cellular_component
Cytoplasm
Cytosol
Plasma Membrane
Postsynaptic Density
Dendrite
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Eukaryotic Initiation Factor 4E Binding
Sequence-specific Double-stranded DNA Binding
Protein Binding
G Protein-coupled Glutamate Receptor Binding
Identical Protein Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Axon Guidance
Regulation Of Smoothened Signaling Pathway
Forebrain Development
Midbrain Development
Positive Regulation Of Embryonic Development
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Protein-containing Complex Assembly
Dopaminergic Neuron Differentiation
Primitive Streak Formation
Positive Regulation Of Gastrulation
Protein Targeting
G Protein-coupled Glutamate Receptor Signaling Pathway
Negative Regulation Of Interleukin-2 Production
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Regulation Of Store-operated Calcium Entry
Pathways
Neurexins and neuroligins
Neurexins and neuroligins
Drugs
Diseases
Anophthalmia and microphthalmia (A/M)
Septo-optic dysplasia
GWAS
Alcohol consumption (
31358974
)
Alcohol consumption (drinks per week) (
30643258
)
Chronotype (
30696823
)
Moderate-to-late spontaneous preterm birth (
31194736
)
Refractive error (
32231278
)
Interacting Genes
43 interacting genes:
APP
ASIC4
ATP6V1G3
ATXN1
AURKC
B4GALNT2
BNIP2
CDK3
CDK4
DMBX1
FOXA2
GPR45
GUCA1B
HIKESHI
HNF1B
HOMER3
HSD3B7
IQGAP1
JPT1
KLF3
LHX1
M1AP
MITF
NAA50
OR1L3
OR6C1
POLDIP3
RBM47
RNASE11
RPS26
RTCA
SMARCB1
SNRPA
TBCEL
TENT5B
TLE4
TMEM11
TNPO2
TRMT10B
ZC3H10
ZDHHC17
ZNF765
ZNHIT1
86 interacting genes:
ABI1
ABI2
ABI3
APP
ARL13B
C1orf116
C4orf17
CCDC120
CCDC141
CCDC187
CDC37
CDK18
CEBPB
CWF19L2
DVL3
DYNLL1
DYNLL2
EAF1
EFHC1
EIF3D
FAM161B
FAM90A1
FAT1
FBXO28
FRYL
GAS8
GGN
GRM5
HOMER1
HOXB5
INCA1
ITPR1
KANK2
KANK4
KDM1A
KRTAP19-7
LHX2
LNX1
LRRC7
LSM14B
MDM1
MEOX1
MFAP1
MIA3
MOS
MSS51
NEBL
NTAQ1
OTX2
PALLD
PAX6
PAX7
PKN1
PLAAT5
POLI
POM121
PPP1R18
PPP1R32
PRCC
PRR35
PSMA1
PSMA2
PSMC5
PSORS1C2
RBM14
RBM22
RUNX1T1
RYR1
SAXO1
SCNM1
SDCBP
SLAIN1
SMR3B
SNRPF
SRPK2
TBC1D22B
TOX2
TRPC1
USP2
WBP2
WIPF1
ZBTB4
ZNF19
ZNF35
ZNF414
ZNF655
Entrez ID
5015
9454
HPRD ID
07190
07270
Ensembl ID
ENSG00000165588
ENSG00000051128
Uniprot IDs
F1T0C9
F1T0D0
F1T0D1
P32243
Q9NSC5
PDB IDs
2P8V
3CVF
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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