HOMER3 and TOX2

Data Source:
BioGRID (two hybrid)

		HOMER3	TOX2
Description		homer scaffold protein 3	TOX high mobility group box family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Dendrite	Nucleus Nucleoplasm
	Molecular Function	Protein Binding G Protein-coupled Glutamate Receptor Binding Identical Protein Binding	Transcription Coactivator Activity Chromatin DNA Binding
	Biological Process	Protein Targeting G Protein-coupled Glutamate Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Colorectal cancer ( 30529582) Conduct disorder (symptom count) ( 20585324) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Red blood cell count ( 32888494 27863252) Refractive error ( 32231278) White blood cell count ( 32888494)
Interacting Genes		86 interacting genes: ABI1 ABI2 ABI3 APP ARL13B C1orf116 C4orf17 CCDC120 CCDC141 CCDC187 CDC37 CDK18 CEBPB CWF19L2 DVL3 DYNLL1 DYNLL2 EAF1 EFHC1 EIF3D FAM161B FAM90A1 FAT1 FBXO28 FRYL GAS8 GGN GRM5 HOMER1 HOXB5 INCA1 ITPR1 KANK2 KANK4 KDM1A KRTAP19-7 LHX2 LNX1 LRRC7 LSM14B MDM1 MEOX1 MFAP1 MIA3 MOS MSS51 NEBL NTAQ1 OTX2 PALLD PAX6 PAX7 PKN1 PLAAT5 POLI POM121 PPP1R18 PPP1R32 PRCC PRR35 PSMA1 PSMA2 PSMC5 PSORS1C2 RBM14 RBM22 RUNX1T1 RYR1 SAXO1 SCNM1 SDCBP SLAIN1 SMR3B SNRPF SRPK2 TBC1D22B TOX2 TRPC1 USP2 WBP2 WIPF1 ZBTB4 ZNF19 ZNF35 ZNF414 ZNF655	24 interacting genes: ANKS1A APP CENPP CSTF2T ENKD1 HCK HOMER3 HSF2BP HSFY1 HSFY2 LGALS4 MFHAS1 NDUFAB1 P4HA3 PHF1 RIBC1 SPG21 TCEA2 TEKT4 TEKT5 TLX3 UNC5CL YPEL3 ZNF461
Entrez ID		9454	84969
HPRD ID		07270	12734
Ensembl ID		ENSG00000051128	ENSG00000124191
Uniprot IDs		Q9NSC5	Q96NM4
PDB IDs		2P8V 3CVF
Enriched GO Terms of Interacting Partners?
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