ATP4B and AGO3

Data Source:
BioGRID (two hybrid)

		ATP4B	AGO3
Description		ATPase H+/K+ transporting subunit beta	argonaute RISC catalytic component 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Sodium:potassium-exchanging ATPase Complex	Condensed Nuclear Chromosome P-body Nucleoplasm Cytoplasm Cytosol Membrane RISC Complex Cytoplasmic Ribonucleoprotein Granule RISC-loading Complex
	Molecular Function	ATPase Activator Activity Protein Binding Potassium:proton Exchanging ATPase Activity	RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Endoribonuclease Activity Protein Binding MiRNA Binding Metal Ion Binding Endoribonuclease Activity, Cleaving MiRNA-paired MRNA
	Biological Process	Cellular Sodium Ion Homeostasis Cell Adhesion Response To Organonitrogen Compound Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Response To Lipopolysaccharide Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane PH Reduction Potassium Ion Import Across Plasma Membrane	MRNA Catabolic Process Wnt Signaling Pathway, Calcium Modulating Pathway RNA Secondary Structure Unwinding Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Pre-miRNA Processing Post-transcriptional Gene Silencing By RNA Production Of MiRNAs Involved In Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation MRNA Cleavage Involved In Gene Silencing By MiRNA MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Regulation Of Megakaryocyte Differentiation Regulation Of Stem Cell Proliferation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic MRNA Cleavage Involved In Gene Silencing By SiRNA Positive Regulation Of NIK/NF-kappaB Signaling
Pathways		Ion transport by P-type ATPases	Pre-NOTCH Transcription and Translation MicroRNA (miRNA) biogenesis Oxidative Stress Induced Senescence Oncogene Induced Senescence Ca2+ pathway Small interfering RNA (siRNA) biogenesis Post-transcriptional silencing by small RNAs TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Transcriptional Regulation by VENTX Regulation of RUNX1 Expression and Activity RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Transcriptional Regulation by MECP2 Estrogen-dependent gene expression Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs		Dexlansoprazole
Diseases
GWAS		Height ( 31562340)
Interacting Genes		6 interacting genes: AGO3 BPGM CCNDBP1 GPR42 STX1A ZC4H2	4 interacting genes: ATP4B ATP6V0D2 BDNF SLC22A2
Entrez ID		496	192669
HPRD ID		00669	09558
Ensembl ID		ENSG00000186009	ENSG00000126070
Uniprot IDs		P51164	B4E1P5 Q9H9G7
PDB IDs			5VM9
Enriched GO Terms of Interacting Partners?
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