AGO3 and ATP4B

Data Source:
BioGRID (two hybrid)

		AGO3	ATP4B
Description		argonaute RISC catalytic component 3	ATPase H+/K+ transporting subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome P-body Nucleoplasm Cytoplasm Cytosol Membrane RISC Complex Cytoplasmic Ribonucleoprotein Granule RISC-loading Complex	Plasma Membrane Sodium:potassium-exchanging ATPase Complex
	Molecular Function	RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Endoribonuclease Activity Protein Binding MiRNA Binding Metal Ion Binding Endoribonuclease Activity, Cleaving MiRNA-paired MRNA	ATPase Activator Activity Protein Binding Potassium:proton Exchanging ATPase Activity
	Biological Process	MRNA Catabolic Process Wnt Signaling Pathway, Calcium Modulating Pathway RNA Secondary Structure Unwinding Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Pre-miRNA Processing Post-transcriptional Gene Silencing By RNA Production Of MiRNAs Involved In Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation MRNA Cleavage Involved In Gene Silencing By MiRNA MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Regulation Of Megakaryocyte Differentiation Regulation Of Stem Cell Proliferation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic MRNA Cleavage Involved In Gene Silencing By SiRNA Positive Regulation Of NIK/NF-kappaB Signaling	Cellular Sodium Ion Homeostasis Cell Adhesion Response To Organonitrogen Compound Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Response To Lipopolysaccharide Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane PH Reduction Potassium Ion Import Across Plasma Membrane
Pathways		Pre-NOTCH Transcription and Translation MicroRNA (miRNA) biogenesis Oxidative Stress Induced Senescence Oncogene Induced Senescence Ca2+ pathway Small interfering RNA (siRNA) biogenesis Post-transcriptional silencing by small RNAs TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Transcriptional Regulation by VENTX Regulation of RUNX1 Expression and Activity RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Transcriptional Regulation by MECP2 Estrogen-dependent gene expression Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	Ion transport by P-type ATPases
Drugs			Dexlansoprazole
Diseases
GWAS			Height ( 31562340)
Interacting Genes		4 interacting genes: ATP4B ATP6V0D2 BDNF SLC22A2	6 interacting genes: AGO3 BPGM CCNDBP1 GPR42 STX1A ZC4H2
Entrez ID		192669	496
HPRD ID		09558	00669
Ensembl ID		ENSG00000126070	ENSG00000186009
Uniprot IDs		B4E1P5 Q9H9G7	P51164
PDB IDs		5VM9
Enriched GO Terms of Interacting Partners?
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