OAT and SLC35F6

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		OAT	SLC35F6
Description		ornithine aminotransferase	solute carrier family 35 member F6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix	Nucleoplasm Mitochondrion Lysosomal Membrane Cytosol Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Ornithine-oxo-acid Transaminase Activity Protein Binding Pyridoxal Phosphate Binding Identical Protein Binding Ornithine(lysine) Transaminase Activity	Protein Binding Transmembrane Transporter Activity
	Biological Process	Visual Perception Cellular Amino Acid Biosynthetic Process Arginine Catabolic Process To Proline Via Ornithine Arginine Catabolic Process To Glutamate L-proline Biosynthetic Process	Positive Regulation Of Cell Population Proliferation Transmembrane Transport Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Pathways		Glutamate and glutamine metabolism
Drugs		Pyridoxal phosphate Ornithine Gabaculine Canaline
Diseases		Ornithinaemia
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		3 interacting genes: NUDT3 SLC35F6 UBQLN4	22 interacting genes: ACP5 ACP6 ALDH2 AQP6 CBARP CERS4 FOLR1 GJA8 GPR152 KIAA0087 KIAA0232 MS4A7 NDUFA4L2 NSG2 OAT PSMG2 SEC11A SEPHS1 SERPINH1 TBPL1 TIMMDC1 TMEM14B
Entrez ID		4942	54978
HPRD ID		02021	12808
Ensembl ID		ENSG00000065154	ENSG00000213699
Uniprot IDs		A0A140VJQ4 P04181	Q8N357
PDB IDs		1GBN 1OAT 2BYJ 2BYL 2CAN 2OAT 5VWO 6HX7 6OIA
Enriched GO Terms of Interacting Partners?
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