OAT and NUDT3

Data Source:
BioGRID (two hybrid)

		OAT	NUDT3
Description		ornithine aminotransferase	nudix hydrolase 3
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix	Nucleus Cytoplasm Cytosol
	Molecular Function	Ornithine-oxo-acid Transaminase Activity Protein Binding Pyridoxal Phosphate Binding Identical Protein Binding Ornithine(lysine) Transaminase Activity	Magnesium Ion Binding Endopolyphosphatase Activity Protein Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity M7G(5')pppN Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity
	Biological Process	Visual Perception Cellular Amino Acid Biosynthetic Process Arginine Catabolic Process To Proline Via Ornithine Arginine Catabolic Process To Glutamate L-proline Biosynthetic Process	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Inositol Phosphate Metabolic Process Diphosphoinositol Polyphosphate Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process
Pathways		Glutamate and glutamine metabolism	Synthesis of pyrophosphates in the cytosol
Drugs		Pyridoxal phosphate Ornithine Gabaculine Canaline
Diseases		Ornithinaemia
GWAS			Atrial fibrillation ( 29892015) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29381148 20935630) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 30604766) Height ( 25429064 19893584 31562340) Hip circumference ( 25673412) Myeloproliferative neoplasms ( 33057200) Refractive error ( 32231278)
Interacting Genes		3 interacting genes: NUDT3 SLC35F6 UBQLN4	36 interacting genes: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1
Entrez ID		4942	11165
HPRD ID		02021	14849
Ensembl ID		ENSG00000065154	ENSG00000272325
Uniprot IDs		A0A140VJQ4 P04181	O95989
PDB IDs		1GBN 1OAT 2BYJ 2BYL 2CAN 2OAT 5VWO 6HX7 6OIA	2FVV 2Q9P 6PCK 6PCL
Enriched GO Terms of Interacting Partners?
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