NRGN and CDON

Data Source:
BioGRID (affinity chromatography technology)

		NRGN	CDON
Description		neurogranin	cell adhesion associated, oncogene regulated
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Trans-Golgi Network Transport Vesicle Membrane Postsynaptic Density Axon Mitochondrial Membrane Neuronal Cell Body Dendritic Spine Head Postsynaptic Membrane Glutamatergic Synapse	Plasma Membrane Integral Component Of Plasma Membrane Collagen-containing Extracellular Matrix
	Molecular Function	Calmodulin Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidic Acid Binding	Protein Binding
	Biological Process	Signal Transduction Nervous System Development Associative Learning Telencephalon Development Postsynaptic Modulation Of Chemical Synaptic Transmission Positive Regulation Of Long-term Synaptic Potentiation	Cell Fate Specification Positive Regulation Of Protein Phosphorylation Lens Development In Camera-type Eye Cell Adhesion Smoothened Signaling Pathway Myoblast Fusion Anterior/posterior Pattern Specification Embryonic Body Morphogenesis Skeletal Muscle Satellite Cell Differentiation Cerebral Cortex Development Regulation Of Protein Binding Positive Regulation Of MAPK Cascade Positive Regulation Of Myoblast Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Muscle Cell Differentiation Embryonic Retina Morphogenesis In Camera-type Eye Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		Long-term potentiation Long-term potentiation	Myogenesis Myogenesis Ligand-receptor interactions Activation of SMO
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 28991256 25056061 19571808 29483656 30285260)	Alzheimer's disease (late onset) ( 22881374) Blood protein levels ( 30072576 29875488 28240269) Cerebral white matter volume ( 31530798) Height ( 31562340) Lung function (FEV1) ( 28166213) Mild to moderate chronic kidney disease ( 31178898) Primary tooth development (time to first tooth eruption) ( 23704328) Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		6 interacting genes: CALM1 EIF5 GLP1R PRKCA PRKCB PRKCG	5 interacting genes: ABL1 BOC CDH15 CDH2 CTNNB1
Entrez ID		4900	50937
HPRD ID		03828	16372
Ensembl ID		ENSG00000154146	ENSG00000064309
Uniprot IDs		A0A024R3M7 Q92686	Q4KMG0
PDB IDs			3D1M 3N1F 3N1Q
Enriched GO Terms of Interacting Partners?
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