NMB and PTPRZ1

Data Source:
HPRD (in vivo)

		NMB	PTPRZ1
Description		neuromedin B	protein tyrosine phosphatase receptor type Z1
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GO Annotations	Cellular Component	Extracellular Region Neuron Projection	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Intrinsic Component Of Plasma Membrane
	Molecular Function	Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuromedin B Receptor Binding	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Integrin Binding Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Glucose Homeostasis Positive Regulation Of Hormone Secretion Negative Regulation Of Hormone Secretion Arachidonic Acid Secretion	Protein Dephosphorylation Central Nervous System Development Learning Or Memory Cytokine-mediated Signaling Pathway Regulation Of Myelination Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Neuron Apoptotic Process Oligodendrocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	Other interleukin signaling
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Creatine kinase levels ( 29403010) P wave terminal force ( 28794112) Schizophrenia ( 29483656)	Hand grip strength ( 27325353) Heel bone mineral density ( 30598549) Lung adenocarcinoma ( 28604730)
Interacting Genes		4 interacting genes: BIRC2 GADD45G NMBR TPP1	13 interacting genes: ADD2 ALK ARHGAP35 CTNNB1 FYN GIT1 HMGB1 IL34 MDK MGAT5B PTN PTPRF TNR
Entrez ID		4828	5803
HPRD ID		01210	01481
Ensembl ID		ENSG00000197696	ENSG00000106278
Uniprot IDs		P08949	B4DFE7 P23471
PDB IDs		1C98 1C9A	3JXF 3S97 5AWX 5H08
Enriched GO Terms of Interacting Partners?
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