NFRKB and ST14

Data Source:
BioGRID (affinity chromatography technology)

		NFRKB	ST14
Description		nuclear factor related to kappaB binding protein	ST14 transmembrane serine protease matriptase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Ino80 Complex	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Extrinsic Component Of Plasma Membrane
	Molecular Function	Protease Binding DNA Binding Protein Binding	Serine-type Endopeptidase Activity Serine-type Peptidase Activity
	Biological Process	DNA Repair DNA Recombination Protein Deubiquitination	Neural Tube Closure Proteolysis Keratinocyte Differentiation Epithelial Cell Morphogenesis Involved In Placental Branching Cornification
Pathways		UCH proteinases DNA Damage Recognition in GG-NER	Formation of the cornified envelope Formation of the cornified envelope
Drugs			Urokinase Benzamidine Camostat
Diseases			Ichthyosis with hypotrichosis
GWAS		High light scatter reticulocyte count ( 32888494) Night sleep phenotypes ( 27126917) Reticulocyte count ( 32888494)	Adverse response to drug ( 30420678) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		4 interacting genes: EPHB3 NFKB1 TRDMT1 UCHL5	17 interacting genes: AKT1 APC CASP8 CDCP1 CDKN2C CHEK2 F2RL1 HGF NOTCH2 PDGFC PHB PLAU RAD51 RGS16 SPINT1 STK11 TGFB1
Entrez ID		4798	6768
HPRD ID		01240	06005
Ensembl ID		ENSG00000170322	ENSG00000149418
Uniprot IDs		A0A024R3K9 Q6P4R8	Q9Y5Y6
PDB IDs		3U21 4UF5 4UF6 4WLP	1EAW 1EAX 2FMV 2GV6 2GV7 3BN9 3NCL 3NPS 3P8F 3P8G 3SO3 4IS5 4ISL 4ISN 4ISO 4JYT 4JZ1 4JZI 4O97 4O9V 4R0I 5LYO 6N4T
Enriched GO Terms of Interacting Partners?
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