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ATP12A and GNAI3
Data Source:
BioGRID
(two hybrid)
ATP12A
GNAI3
Description
ATPase H+/K+ transporting non-gastric alpha2 subunit
G protein subunit alpha i3
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Potassium:proton Exchanging ATPase Complex
Golgi Membrane
Cytoplasm
Lysosomal Membrane
Endoplasmic Reticulum Membrane
Centrosome
Heterotrimeric G-protein Complex
Plasma Membrane
Membrane
Midbody
Zymogen Granule
Membrane Raft
Extracellular Exosome
Molecular Function
P-type Sodium:potassium-exchanging ATPase Activity
ATP Binding
Potassium:proton Exchanging ATPase Activity
Metal Ion Binding
G Protein-coupled Receptor Binding
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
Protein Domain Specific Binding
G-protein Beta/gamma-subunit Complex Binding
G Protein-coupled Serotonin Receptor Binding
GTPase Activating Protein Binding
Metal Ion Binding
Biological Process
Cellular Sodium Ion Homeostasis
Establishment Or Maintenance Of Transmembrane Electrochemical Gradient
Cellular Potassium Ion Homeostasis
Ion Transmembrane Transport
Sodium Ion Export Across Plasma Membrane
Proton Transmembrane Transport
Potassium Ion Import Across Plasma Membrane
Protein Folding
Vesicle Fusion
Cell Cycle
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
Dopamine Receptor Signaling Pathway
Brain Development
Positive Regulation Of Macroautophagy
Positive Regulation Of Superoxide Anion Generation
Positive Regulation Of NAD(P)H Oxidase Activity
GTP Metabolic Process
Cell Division
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Apoptotic Signaling Pathway
Pathways
Ion transport by P-type ATPases
PLC beta mediated events
PLC beta mediated events
Adenylate cyclase inhibitory pathway
Adenylate cyclase inhibitory pathway
G-protein activation
ADP signalling through P2Y purinoceptor 12
G alpha (s) signalling events
G alpha (i) signalling events
G alpha (i) signalling events
G alpha (z) signalling events
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS
Diastolic blood pressure (
30224653
)
Meconium ileus in cystic fibrosis (
30807572
)
Obesity-related traits (
23251661
)
Childhood body mass index (
33045005
)
Major depressive disorder (
20125088
)
Interacting Genes
3 interacting genes:
GNAI3
NPY
PPIB
43 interacting genes:
AGTR2
ATP12A
CCDC88A
CCDC88C
CCR5
CD48
CD59
CNR1
CXCR2
DRD2
GNB2
GNB4
GPSM1
GPSM2
GPSM3
HTR1A
LPAR1
MTNR1A
MTNR1B
NGB
NUCB1
NUCB2
PCP2
PHF24
PRKAR2B
PTPRU
RANGAP1
RGS10
RGS12
RGS14
RGS16
RGS17
RGS18
RGS19
RGS2
RGS20
RGS3
RGS5
RGS7
RIC8A
S1PR1
SOX30
TSHR
Entrez ID
479
2773
HPRD ID
01667
00765
Ensembl ID
ENSG00000075673
ENSG00000065135
Uniprot IDs
B4E0R9
P54707
P08754
PDB IDs
2IHB
2ODE
2V4Z
4G5O
4G5R
4G5S
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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