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ATP1A1 and FXYD2
Data Source:
HPRD
(in vivo)
ATP1A1
FXYD2
Description
ATPase Na+/K+ transporting subunit alpha 1
FXYD domain containing ion transport regulator 2
Image
No pdb structure
GO Annotations
Cellular Component
Endosome
Endoplasmic Reticulum
Golgi Apparatus
Plasma Membrane
Sodium:potassium-exchanging ATPase Complex
Caveola
Postsynaptic Density
Intercalated Disc
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Lateral Plasma Membrane
T-tubule
Organelle Membrane
Protein-containing Complex
Sperm Flagellum
Sarcolemma
Melanosome
Membrane Raft
Photoreceptor Inner Segment Membrane
Extracellular Exosome
Extracellular Vesicle
Plasma Membrane
Sodium:potassium-exchanging ATPase Complex
Extracellular Exosome
Molecular Function
P-type Sodium:potassium-exchanging ATPase Activity
Protein Binding
ATP Binding
Phosphatase Activity
Protein Kinase Binding
Protein Domain Specific Binding
Ankyrin Binding
Potassium Ion Binding
Sodium Ion Binding
ADP Binding
Phosphatidylinositol 3-kinase Binding
Protein Heterodimerization Activity
Chaperone Binding
Steroid Hormone Binding
ATPase Activator Activity
Sodium Channel Regulator Activity
Protein-macromolecule Adaptor Activity
Ion Channel Regulator Activity
Biological Process
Regulation Of The Force Of Heart Contraction
Regulation Of Sodium Ion Transport
Cellular Sodium Ion Homeostasis
Regulation Of Blood Pressure
Establishment Or Maintenance Of Transmembrane Electrochemical Gradient
Dephosphorylation
Cellular Potassium Ion Homeostasis
Negative Regulation Of Glucocorticoid Biosynthetic Process
Ion Transmembrane Transport
Sodium Ion Export Across Plasma Membrane
Response To Drug
Negative Regulation Of Heart Contraction
Positive Regulation Of Heart Contraction
Positive Regulation Of Striated Muscle Contraction
Relaxation Of Cardiac Muscle
Membrane Hyperpolarization
Cellular Response To Mechanical Stimulus
Cellular Response To Steroid Hormone Stimulus
Cardiac Muscle Cell Action Potential Involved In Contraction
Regulation Of Cardiac Muscle Cell Contraction
Membrane Repolarization
Membrane Repolarization During Cardiac Muscle Cell Action Potential
Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Proton Transmembrane Transport
Response To Glycoside
Regulation Of Cardiac Conduction
Potassium Ion Import Across Plasma Membrane
Positive Regulation Of ATPase Activity
Ion Transmembrane Transport
Sodium Ion Export Across Plasma Membrane
Transmembrane Transport
Positive Regulation Of Sodium:potassium-exchanging ATPase Activity
Regulation Of Cardiac Conduction
Potassium Ion Import Across Plasma Membrane
Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways
Ion homeostasis
Ion transport by P-type ATPases
Potential therapeutics for SARS
Ion homeostasis
Ion transport by P-type ATPases
Potential therapeutics for SARS
Drugs
Digoxin
Acetyldigitoxin
Hydroflumethiazide
Etacrynic acid
Trichlormethiazide
Deslanoside
Ouabain
Diazoxide
Bretylium
Ciclopirox
Bepridil
Potassium cation
Aluminium
Magnesium cation
Digitoxin
Almitrine
Istaroxime
Magnesium acetate
Potassium acetate
Potassium sulfate
Potassium
Magnesium levulinate
Magnesium lactate
Aluminium phosphate
Aluminum acetate
Cyclothiazide
Thimerosal
Diseases
GWAS
Coffee consumption (
29367735
)
Macular thickness (
30535121
)
Hippocampal volume in Alzheimer's disease dementia (
29274321
)
Myopia (
27182965
)
Refractive error (
32231278
)
Interacting Genes
18 interacting genes:
A2M
ADD1
CFL1
EGFR
EZH2
FXYD1
FXYD2
FXYD7
GPR35
HGS
MAPK1
MAPK3
NDRG1
PRKCA
SNAPIN
TPT1
ZNRF1
ZNRF2
5 interacting genes:
ATP1A1
ERGIC3
SGTA
SLC22A1
SLC22A2
Entrez ID
476
486
HPRD ID
01662
03487
Ensembl ID
ENSG00000163399
ENSG00000137731
Uniprot IDs
P05023
P54710
PDB IDs
2MKV
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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