NEO1 and PITPNA

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		NEO1	PITPNA
Description		neogenin 1	phosphatidylinositol transfer protein alpha
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GO Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Plasma Membrane Protein Complex	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Signaling Receptor Activity Co-receptor Binding	Protein Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transfer Activity Phosphatidylcholine Binding Phosphatidylinositol Binding Phosphatidylcholine Transfer Activity Phosphatidylglycerol Binding
	Biological Process	Cell Adhesion Axon Guidance Positive Regulation Of BMP Signaling Pathway Iron Ion Homeostasis	Lipid Metabolic Process Visual Perception Phospholipid Transport Interleukin-12-mediated Signaling Pathway Intermembrane Lipid Transfer
Pathways		Netrin-1 signaling Myogenesis	Role of second messengers in netrin-1 signaling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			1,2-diacyl-sn-glycero-3-phosphoinositol (Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide
Diseases
GWAS		Adventurousness ( 30643258) Blood protein levels ( 30072576 29875488) Brain morphology (MOSTest) ( 32665545) Dentures ( 31235808) Face memory ( 31596458) Heart rate variability traits (pvRSA/HF) ( 28613276) Heart rate variability traits (RMSSD) ( 28613276) Heart rate variability traits (SDNN) ( 28613276) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Nickel levels ( 26025379) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Red cell distribution width ( 32888494) Resting heart rate ( 27798624) Urate levels ( 31578528)	Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
Interacting Genes		6 interacting genes: MTDH NTN1 NTN3 PITPNA PTK2 TTN	8 interacting genes: CSNK2B DCC EGFR NEO1 PI4KA PIK3C3 PLCG1 SCP2
Entrez ID		4756	5306
HPRD ID		03549	02548
Ensembl ID		ENSG00000067141	ENSG00000174238
Uniprot IDs		Q59FP8 Q92859	Q00169 V9HWC5
PDB IDs		1X5F 1X5G 1X5H 1X5I 1X5J 1X5K 3P4L	1UW5
Enriched GO Terms of Interacting Partners?
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