NEFM and MINK1

Data Source:
HPRD (two hybrid)

		NEFM	MINK1
Description		neurofilament medium	misshapen like kinase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Neurofilament Axon Intermediate Filament Cytoskeleton Neurofibrillary Tangle	Cytoplasm Golgi Apparatus Cytosol Postsynaptic Density Axon Dendrite Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Microtubule Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Neurofilament Bundle Assembly	MAPK Cascade Regulation Of Cell-matrix Adhesion Protein Phosphorylation JNK Cascade Chemical Synaptic Transmission Multicellular Organism Development Regulation Of Cell-cell Adhesion Microvillus Assembly Regulation Of Cell Migration Stress-activated Protein Kinase Signaling Cascade Actin Cytoskeleton Reorganization Activation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Protein Autophosphorylation Neuron Projection Morphogenesis Dendrite Morphogenesis Positive Regulation Of P38MAPK Cascade Regulation Of AMPA Receptor Activity
Pathways			Oxidative Stress Induced Senescence
Drugs			Fostamatinib
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Fear of minor pain ( 28701861) Idiopathic dilated cardiomyopathy ( 29495422) Interleukin-6 levels ( 22205395) Metabolite levels ( 23823483)	Intracranial aneurysm ( 30823506) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Metabolite levels (lipid measures) ( 27005778) Monocyte count ( 32888494) Multiple sclerosis ( 31604244) Neutrophil percentage of white cells ( 32888494) PR interval ( 32439900)
Interacting Genes		12 interacting genes: APOE DISC1 DRD2 FOS MINK1 NEFH NEFL RB1 SMAD2 STXBP1 TNIK VIM	14 interacting genes: ABI1 ACTA2 CALM3 CASKIN1 KIFAP3 MAP1B NCK1 NEDD4L NEFM PKP4 SPTBN2 TUBA1B YWHAB YWHAZ
Entrez ID		4741	50488
HPRD ID		01205	11366
Ensembl ID		ENSG00000104722	ENSG00000141503
Uniprot IDs		P07197 Q9UK51	Q8N4C8
PDB IDs
Enriched GO Terms of Interacting Partners?
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