RPL10A and SGO1

Data Source:
HPRD (in vivo)

		RPL10A	SGO1
Description		ribosomal protein L10a	shugoshin 1
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GO Annotations	Cellular Component	Nucleus Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome Extracellular Exosome	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Condensed Chromosome, Centromeric Region Spindle Pole Nucleoplasm Centrosome Cytosol
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	Protein Binding Kinase Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of LSU-rRNA Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Mitotic Sister Chromatid Segregation Chromosome Segregation Attachment Of Spindle Microtubules To Kinetochore Centriole-centriole Cohesion Meiotic Chromosome Segregation Homologous Chromosome Segregation Meiotic Sister Chromatid Cohesion Cell Division Mitotic Sister Chromatid Cohesion, Centromeric
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: ACTB DUX4 PTEN RGS17 SGO1 SRPRA YWHAQ	20 interacting genes: CDCA8 LRRC59 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKDC RPL10A RPL28 RPL7 RPL7A RPLP1 SET XRCC5 XRCC6
Entrez ID		4736	151648
HPRD ID		10199	12377
Ensembl ID		ENSG00000198755	ENSG00000129810
Uniprot IDs		A0A024RCW3 P62906	A0A024R2J4 B5BUA4 Q5FBB7
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6LQM 6LSR 6LU8 6OLG 6QZP 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO	3FGA 3Q6S 4A0I
Enriched GO Terms of Interacting Partners?
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