NDUFB8 and EIF2B3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NDUFB8	EIF2B3
Description		NADH:ubiquinone oxidoreductase subunit B8	eukaryotic translation initiation factor 2B subunit gamma
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix Endoplasmic Reticulum Integral Component Of Membrane	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex Guanyl-nucleotide Exchange Factor Complex
	Molecular Function	NADH Dehydrogenase (ubiquinone) Activity	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly	Cytoplasmic Translational Initiation Translational Initiation Response To Heat Response To Glucose Oligodendrocyte Development Hippocampus Development Response To Peptide Hormone Regulation Of Catalytic Activity T Cell Receptor Signaling Pathway
Pathways		Mitochondrial protein import Mitochondrial protein import Respiratory electron transport Complex I biogenesis	Recycling of eIF2:GDP
Drugs		NADH
Diseases			Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS		Brain morphology (MOSTest) ( 32665545) Palmitoleic acid (16:1n-7) levels ( 23362303)	Platelet distribution width ( 32888494)
Interacting Genes		6 interacting genes: ATP6V0D2 CACNA1A EIF2B3 PFN2 PIM2 ZAP70	5 interacting genes: EIF2S1 EIF2S2 GOLM1 NDUFB8 STC2
Entrez ID		4714	8891
HPRD ID		11886	09379
Ensembl ID		ENSG00000166136	ENSG00000070785
Uniprot IDs		O95169	Q9HA31 Q9NR50
PDB IDs		5XTC 5XTD 5XTH 5XTI	6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z
Enriched GO Terms of Interacting Partners?
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