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EIF2B3

Description eukaryotic translation initiation factor 2B subunit gamma
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
  • Eukaryotic Translation Initiation Factor 2B Complex
  • Guanyl-nucleotide Exchange Factor Complex
Molecular Function
  • Translation Initiation Factor Activity
  • Guanyl-nucleotide Exchange Factor Activity
  • Protein Binding
  • Translation Factor Activity, RNA Binding
Biological Process
  • Cytoplasmic Translational Initiation
  • Translational Initiation
  • Response To Heat
  • Response To Glucose
  • Oligodendrocyte Development
  • Hippocampus Development
  • Response To Peptide Hormone
  • Regulation Of Catalytic Activity
  • T Cell Receptor Signaling Pathway
Pathways
  • Recycling of eIF2:GDP
Drugs
Diseases
  • Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS
  • Platelet distribution width ( 32888494)
Novel Interacting Genes 3 novel interacting genes: IPO13 KDM4A ST3GAL3
Interacting Genes 5 interacting genes: EIF2S1 EIF2S2 GOLM1 NDUFB8 STC2
Entrez ID 8891
HPRD ID 09379
Ensembl ID ENSG00000070785
Uniprot IDs Q9HA31 Q9NR50
PDB IDs 6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025