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ATF3 and BATF
Data Source:
BioGRID
(fluorescent resonance energy transfer, fluorescent resonance energy transfer)
ATF3
BATF
Description
activating transcription factor 3
basic leucine zipper ATF-like transcription factor
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Nucleolus
CHOP-ATF3 Complex
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific DNA Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Gluconeogenesis
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Cell Population Proliferation
Cellular Response To Amino Acid Starvation
Skeletal Muscle Cell Differentiation
PERK-mediated Unfolded Protein Response
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Arsenic-containing Substance
Negative Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of TRAIL-activated Apoptotic Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Cytokine Production
Lymphoid Progenitor Cell Differentiation
Regulation Of Transcription By RNA Polymerase II
Cellular Response To DNA Damage Stimulus
Cytokine-mediated Signaling Pathway
DNA Damage Response, Signal Transduction By P53 Class Mediator
Defense Response To Protozoan
Myeloid Dendritic Cell Differentiation
T-helper 2 Cell Differentiation
Isotype Switching
Positive Regulation Of Transcription By RNA Polymerase II
Hematopoietic Stem Cell Differentiation
T-helper 17 Cell Differentiation
T-helper 17 Cell Lineage Commitment
Pathways
ATF4 activates genes in response to endoplasmic reticulum stress
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Interleukin-4 and Interleukin-13 signaling
Drugs
Pseudoephedrine
Diseases
GWAS
Blood cell traits (multivariate analysis) (
31080455
)
Cerebral amyloid deposition (PET imaging) (
26252872
)
Coronary artery disease (
29212778
)
Thiopurine-induced leukopenia in inflammatory bowel disease (conditioned on rs116855232) (
29923122
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction (
31806883
)
Multiple sclerosis (
31604244
24076602
21833088
)
Rheumatoid arthritis (
20453842
)
Interacting Genes
46 interacting genes:
APPL2
ATF2
ATF4
BATF
BATF3
CEBPA
CEBPE
CEBPG
CREB3
CREBBP
CRK
DBP
DDIT3
DNMT3L
DOK5
FGFR3
FOS
FOSL1
HDAC1
HDAC3
HDAC4
HDAC5
HDAC6
ID3
IGSF21
JUN
JUND
KAT5
LRIF1
MAFF
MAFG
NFKB1
NUF2
PDX1
POLR3D
SH2D1A
SMAD3
SRA1
SS18L1
STAT1
STAT3
SUV39H1
TP53
TP73
UBE2I
ZNF212
21 interacting genes:
ATF2
ATF3
ATF4
BATF3
CEBPA
CEBPE
CEBPG
COX8A
DBP
DDIT3
EPAS1
FOS
GOPC
IFI35
IRF4
JUN
JUNB
JUND
KDM1A
NFIL3
SNAPC5
Entrez ID
467
10538
HPRD ID
04395
09820
Ensembl ID
ENSG00000162772
ENSG00000156127
Uniprot IDs
P18847
Q16520
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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