MYOD1 and ID2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vitro)

		MYOD1	ID2
Description		myogenic differentiation 1	inhibitor of DNA binding 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Euchromatin Nucleus Nucleoplasm Transcription Regulator Complex Myofibril	Euchromatin Nucleus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding Nuclear Hormone Receptor Binding Protein Homodimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding Promoter-specific Chromatin Binding	RNA Polymerase II Activating Transcription Factor Binding Protein Binding Ion Channel Binding Protein Dimerization Activity Transcription Regulator Activity Transcription Regulator Inhibitor Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Muscle Organ Development Myoblast Fate Determination Skeletal Muscle Tissue Development Myoblast Fusion Cellular Response To Starvation Myotube Cell Development Myotube Differentiation Involved In Skeletal Muscle Regeneration Negative Regulation Of Chromatin Binding Skeletal Muscle Cell Differentiation Muscle Cell Fate Commitment Positive Regulation Of Skeletal Muscle Tissue Regeneration Regulation Of RNA Splicing Skeletal Muscle Fiber Adaptation Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Binding Positive Regulation Of Muscle Cell Differentiation Cellular Response To Tumor Necrosis Factor Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Oxygen Levels Positive Regulation Of Myoblast Fusion Positive Regulation Of SnRNA Transcription By RNA Polymerase II Negative Regulation Of Myoblast Proliferation	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Lipid Metabolic Process Cell Differentiation Circadian Regulation Of Gene Expression Mammary Gland Epithelial Cell Proliferation Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of DNA-binding Transcription Factor Activity Locomotor Rhythm Regulation Of Neuron Differentiation Positive Regulation Of Blood Pressure Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Neuron Fate Commitment Negative Regulation Of Muscle Cell Differentiation Mammary Gland Alveolus Development Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Endodermal Digestive Tract Morphogenesis Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Senescence Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Neural Precursor Cell Proliferation
Pathways		Myogenesis Myogenesis	NGF-stimulated transcription
Drugs
Diseases
GWAS		Body mass index ( 26426971) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)	Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31959851 27182965) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Cognitive decline rate in late mild cognitive impairment ( 26252872) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732) IgE levels ( 22075330) Itch intensity from mosquito bite ( 28199695) Mean corpuscular volume ( 28017375) PR interval ( 29127183 30046033 32439900 31217584) Self-reported allergy ( 23817569)
Interacting Genes		67 interacting genes: AP1M1 ASCL3 BHLHA15 BHLHE40 BHLHE41 C2orf88 CALM1 CALM2 CALM3 CARM1 CDC34 CDK2 CDK4 CDKN1C CIB2 CREBBP CSRP3 ELSPBP1 EP300 EXOC3L1 FBXO32 FIGLA HAND1 HDAC1 HEY1 HSP90AA1 ID1 ID2 ID3 ID4 IFRD1 IGFN1 JUN KAT2B KAT5 KPNA3 LMO4 MDFI MEF2A MEF2C MOS MYOCD NCOR1 NCOR2 NR2F2 PHB2 POLR2G PRKCA PRMT5 PSMD4 PSME2 RB1 RORA RUNX1 RXRA SETD3 SMAD3 SMAD4 SMAD7 SP1 SRF STAT3 SUV39H1 TCF21 TCF3 TCF4 TWIST1	53 interacting genes: ADD1 ASB4 ASCL4 C22orf39 CDK2 DYRK1A DYRK1B ELK1 ELK3 ELK4 ELOC ENKD1 FANCL FNDC11 FRS3 GATA4 GFUS HES1 IFI16 KDM1A LRIF1 MAPK1 MAPK3 MAPK8 MSC MSGN1 MYF5 MYF6 MYOD1 MYOG NEDD9 NR0B2 PAX2 PAX5 PAX8 PICK1 PPP1CA PRMT6 RB1 RBL1 RBL2 RBM48 RHOU RIN3 SREBF1 SUV39H1 SUV39H2 TCF12 TCF3 TCF4 TCHP TNS2 UNC119
Entrez ID		4654	3398
HPRD ID		01166	02664
Ensembl ID		ENSG00000129152	ENSG00000115738
Uniprot IDs		P15172	Q02363 Q53T66
PDB IDs			4AYA
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?