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MYOD1 and CARM1
Data Source:
BioGRID
(pull down)
MYOD1
CARM1
Description
myogenic differentiation 1
coactivator associated arginine methyltransferase 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Euchromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Myofibril
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Activating Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
Protein Binding
Chromatin DNA Binding
Ubiquitin Protein Ligase Binding
Nuclear Hormone Receptor Binding
Protein Homodimerization Activity
E-box Binding
Sequence-specific Double-stranded DNA Binding
Promoter-specific Chromatin Binding
Transcription Regulatory Region Sequence-specific DNA Binding
Transcription Coactivator Activity
Protein Binding
Beta-catenin Binding
Protein Methyltransferase Activity
Histone-arginine N-methyltransferase Activity
Protein-arginine N-methyltransferase Activity
Nuclear Receptor Coactivator Activity
Protein-arginine Omega-N Asymmetric Methyltransferase Activity
Histone Methyltransferase Activity (H3-R17 Specific)
Histone Methyltransferase Activity
Lysine-acetylated Histone Binding
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Regulation Of Transcription By RNA Polymerase II
Protein Phosphorylation
Muscle Organ Development
Myoblast Fate Determination
Skeletal Muscle Tissue Development
Myoblast Fusion
Cellular Response To Starvation
Myotube Cell Development
Myotube Differentiation Involved In Skeletal Muscle Regeneration
Negative Regulation Of Chromatin Binding
Skeletal Muscle Cell Differentiation
Muscle Cell Fate Commitment
Positive Regulation Of Skeletal Muscle Tissue Regeneration
Regulation Of RNA Splicing
Skeletal Muscle Fiber Adaptation
Histone H3 Acetylation
Histone H4 Acetylation
Positive Regulation Of Myoblast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Skeletal Muscle Fiber Development
Positive Regulation Of Skeletal Muscle Fiber Development
Positive Regulation Of Binding
Positive Regulation Of Muscle Cell Differentiation
Cellular Response To Tumor Necrosis Factor
Cellular Response To Glucocorticoid Stimulus
Cellular Response To Estradiol Stimulus
Cellular Response To Oxygen Levels
Positive Regulation Of Myoblast Fusion
Positive Regulation Of SnRNA Transcription By RNA Polymerase II
Negative Regulation Of Myoblast Proliferation
Regulation Of Transcription, DNA-templated
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Aging
Positive Regulation Of Cell Population Proliferation
Viral Process
Histone Methylation
Regulation Of Lipid Metabolic Process
Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine
Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Histone H3-R2 Methylation
Histone H3-R17 Methylation
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Response To CAMP
Regulation Of MRNA Binding
Negative Regulation Of Dendrite Development
Pathways
Myogenesis
Myogenesis
RORA activates gene expression
BMAL1:CLOCK,NPAS2 activates circadian gene expression
PPARA activates gene expression
PPARA activates gene expression
Transcriptional activation of mitochondrial biogenesis
Activation of gene expression by SREBF (SREBP)
RMTs methylate histone arginines
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by PPARalpha
Circadian Clock
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Estrogen-dependent gene expression
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Metabolite levels (
23823483
)
Night sleep phenotypes (
27126917
)
C-reactive protein levels or LDL-cholesterol levels (pleiotropy) (
27286809
)
C-reactive protein levels or total cholesterol levels (pleiotropy) (
27286809
)
Psoriasis (
25574825
23143594
)
Psoriasis vulgaris (
26626624
)
Interacting Genes
67 interacting genes:
AP1M1
ASCL3
BHLHA15
BHLHE40
BHLHE41
C2orf88
CALM1
CALM2
CALM3
CARM1
CDC34
CDK2
CDK4
CDKN1C
CIB2
CREBBP
CSRP3
ELSPBP1
EP300
EXOC3L1
FBXO32
FIGLA
HAND1
HDAC1
HEY1
HSP90AA1
ID1
ID2
ID3
ID4
IFRD1
IGFN1
JUN
KAT2B
KAT5
KPNA3
LMO4
MDFI
MEF2A
MEF2C
MOS
MYOCD
NCOR1
NCOR2
NR2F2
PHB2
POLR2G
PRKCA
PRMT5
PSMD4
PSME2
RB1
RORA
RUNX1
RXRA
SETD3
SMAD3
SMAD4
SMAD7
SP1
SRF
STAT3
SUV39H1
TCF21
TCF3
TCF4
TWIST1
33 interacting genes:
AXIN1
CREBBP
CTNNB1
DAXX
DNAJA3
DZIP3
ELAVL1
EP300
FLII
FOS
GRIP1
H3-3A
H3-3B
H3C1
MALT1
MEF2D
MYOD1
MYOG
NCOA1
NCOA2
NUDT21
PABPC1
PABPN1
PRMT8
PYGO1
QKI
RABGAP1
RELA
SMARCA4
SPAG8
SRCAP
TP53
UBE2I
Entrez ID
4654
10498
HPRD ID
01166
09158
Ensembl ID
ENSG00000129152
ENSG00000142453
Uniprot IDs
P15172
Q86X55
PDB IDs
2Y1W
2Y1X
4IKP
5DWQ
5DX0
5DX1
5DX8
5DXA
5DXJ
5U4X
6ARJ
6ARV
6D2L
6DVR
6IZQ
6S70
6S71
6S74
6S77
6S79
6S7A
6S7B
6S7C
Enriched GO Terms of Interacting Partners
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