MYO9B and LRRC41

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MYO9B	LRRC41
Description		myosin IXB	leucine rich repeat containing 41
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Actin Filament Cell Cortex Actin Cytoskeleton Membrane Myosin Complex Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Cytosol Membrane
	Molecular Function	Microfilament Motor Activity Actin Binding GTPase Activator Activity Protein Binding Calmodulin Binding ATP Binding ATPase Activity Small GTPase Binding Protein Homodimerization Activity ADP Binding Metal Ion Binding Roundabout Binding	Protein Binding
	Biological Process	Rho Protein Signal Transduction Actin Filament-based Movement ARF Protein Signal Transduction Regulation Of Rho Protein Signal Transduction Roundabout Signaling Pathway Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Protein Ubiquitination Post-translational Protein Modification
Pathways		Rho GTPase cycle Regulation of actin dynamics for phagocytic cup formation SLIT2:ROBO1 increases RHOA activity FCGR3A-mediated phagocytosis	Neddylation RHOBTB3 ATPase cycle Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Asthma ( 32296059) Coronary artery disease ( 29212778 33020668) Diastolic blood pressure ( 27841878) Glycated hemoglobin levels ( 24647736 28898252) Height ( 20881960 31562340 29782485) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 29403010 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Night sleep phenotypes ( 27126917) Platelet count ( 29403010 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494 27863252) Prostate cancer ( 29892016) Prostate cancer (early onset) ( 29892016) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Selective IgA deficiency ( 27723758) Systolic blood pressure ( 27841878 30578418) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Waist-to-hip ratio adjusted for BMI ( 28552196)	Body mass index ( 26426971)
Interacting Genes		6 interacting genes: ACTA1 ARFGEF1 CALM1 LRRC41 MOB4 PKN2	10 interacting genes: CYSRT1 ELOB ELOC FHL5 KRT31 KRT34 KRTAP3-1 KRTAP6-2 MYO9B RBPMS
Entrez ID		4650	10489
HPRD ID		03677	10102
Ensembl ID		ENSG00000099331	ENSG00000132128
Uniprot IDs		B0I1T6 Q13459 Q4LE74 Q8WVD2	Q15345
PDB IDs		5C5S 5HPY
Enriched GO Terms of Interacting Partners?
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