MYH10 and UBL4A

Data Source:
BioGRID (proximity labelling technology)

		MYH10	UBL4A
Description		myosin heavy chain 10	ubiquitin like 4A
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GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytosol Polysome Cell Cortex Myosin Complex Myosin II Complex Lamellipodium Midbody Cleavage Furrow Actomyosin Extracellular Exosome Myosin II Filament	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane BAT3 Complex
	Molecular Function	Microfilament Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding ATPase Activity Actin-dependent ATPase Activity RNA Stem-loop Binding ADP Binding MRNA 5'-UTR Binding Actin Filament Binding	Protein Binding Ubiquitin-like Protein Transferase Activity Chaperone Binding
	Biological Process	Mitotic Cytokinesis Cell Adhesion Regulation Of Cell Shape Actin Filament-based Movement Actomyosin Structure Organization Positive Regulation Of Protein Secretion Modification Of Postsynaptic Actin Cytoskeleton	Cellular Protein Modification Process Protein Phosphopantetheinylation Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Type 2 diabetes ( 30130595)	Neutrophil count ( 32888494)
Interacting Genes		11 interacting genes: APC BCAP31 DUX4 ECPAS MYH9 PBX1 PTEN S100A4 YWHAE YWHAG ZNF512B	14 interacting genes: AMFR APP CDCA7L ERP27 MEOX2 PER2 RNF126 S100P SEC61B SGTA SGTB TRAF4 TRIM54 USP13
Entrez ID		4628	8266
HPRD ID		01178	02417
Ensembl ID		ENSG00000133026	ENSG00000102178
Uniprot IDs		G1UI33 P35580	P11441
PDB IDs		4PD3	2DZI 4WWR 4X86
Enriched GO Terms of Interacting Partners?
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