PRMT7 and DIO3

Data Source:
BioGRID (pull down)

		PRMT7	DIO3
Description		protein arginine methyltransferase 7	iodothyronine deiodinase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytosol	Plasma Membrane Endosome Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity [myelin Basic Protein]-arginine N-methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Histone Binding Ribonucleoprotein Complex Binding Histone Methyltransferase Activity (H4-R3 Specific)	Thyroxine 5'-deiodinase Activity Thyroxine 5-deiodinase Activity
	Biological Process	Spliceosomal SnRNP Assembly Regulation Of Gene Expression By Genetic Imprinting Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Cell Differentiation Histone Arginine Methylation DNA Methylation Involved In Gamete Generation Regulation Of Protein Binding Histone H4-R3 Methylation	Thyroid Hormone Generation Positive Regulation Of Multicellular Organism Growth Thyroid Hormone Metabolic Process Thyroid Hormone Catabolic Process Hormone Biosynthetic Process Negative Regulation Of Eye Photoreceptor Cell Development Retinal Cone Cell Development Retinal Cone Cell Apoptotic Process
Pathways		RMTs methylate histone arginines	Regulation of thyroid hormone activity
Drugs			Iopodic acid
Diseases
GWAS		Birth weight ( 31043758) Body mass index ( 28892062 25673413) Magnesium levels ( 20700443) Offspring birth weight ( 31043758) Refractive error ( 32231278) Schizophrenia ( 31579629) Serum metabolite levels ( 23093944) Weight ( 28552196)	Metabolite levels ( 23823483) Pulse pressure ( 30224653) Type 1 diabetes ( 19966805)
Interacting Genes		13 interacting genes: CTCFL DIO3 EIF2S1 H2AC20 H3-5 H3C1 H4C1 MNDA NFKBID POT1 SNRPB ZBTB24 ZNF438	3 interacting genes: APP PRMT5 PRMT7
Entrez ID		54496	1735
HPRD ID		15174	11867
Ensembl ID		ENSG00000132600	ENSG00000197406
Uniprot IDs		A0A024R726 Q9NVM4	P55073 Q86TU3
PDB IDs
Enriched GO Terms of Interacting Partners?
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