MPG and RAD23A

Data Source:
HPRD (in vitro)

		MPG	RAD23A
Description		N-methylpurine DNA glycosylase	RAD23 homolog A, nucleotide excision repair protein
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Mitochondrial Nucleoid	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex Centriolar Satellite Intracellular Membrane-bounded Organelle
	Molecular Function	Damaged DNA Binding Alkylbase DNA N-glycosylase Activity Protein Binding DNA-3-methyladenine Glycosylase Activity DNA N-glycosylase Activity DNA-7-methylguanine Glycosylase Activity DNA-7-methyladenine Glycosylase Activity DNA-3-methylguanine Glycosylase Activity	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Kinase Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Proteasome Binding Ubiquitin-specific Protease Binding
	Biological Process	Base-excision Repair DNA Dealkylation Involved In DNA Repair Depurination	Nucleotide-excision Repair Viral Process Protein Deubiquitination Protein Destabilization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Cell Cycle
Pathways		Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Displacement of DNA glycosylase by APEX1	Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER
Drugs		Cisplatin Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576) Glioblastoma ( 28346443) Hemoglobin levels ( 26366553) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell traits ( 23446634)	Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		13 interacting genes: APP CRK EP300 ESR1 FBXO7 GPR182 HSD17B14 MLH1 RAD23A RAD23B RXRA TERF2IP THRB	76 interacting genes: A2M ADRM1 ANKRD40 ATXN3 ATXN7 CCNA2 CDC37 CHEK1 CNTROB CREBBP DAZAP2 DBI ECSIT EP300 EWSR1 FILIP1 GTF2H1 HSPB1 IFIT3 IFIT5 KRTAP12-2 LOXL4 MAP3K1 MAST1 MDM2 MINDY3 MKRN1 MPG NEDD8 NGLY1 NUTM2F PDE6D PHAX PI4K2A PRKN PSEN1 PSMC5 PSMD4 RABGEF1 REL RNF115 RNF32 RNF41 RPN1 RPS27A SH3RF1 SMURF1 SQSTM1 TNFAIP3 TRAF2 TRAF3 TRAF5 TRAF6 TRIM39 TRIM50 TRIM54 TRIM55 TRIM8 TRIP6 UBA52 UBB UBC UBE3A UBE4B UBL7 UBQLN2 UBQLN4 UBXN1 UIMC1 USP25 VAV2 XPC ZBTB26 ZBTB44 ZBTB8A ZFAND6
Entrez ID		4350	5886
HPRD ID		06766	07191
Ensembl ID		ENSG00000103152	ENSG00000179262
Uniprot IDs		P29372 Q1W6H1	A0A024R7G8 A8K1J3 P54725
PDB IDs		1BNK 1EWN 1F4R 1F6O 3QI5 3UBY	1DV0 1F4I 1IFY 1OQY 1P98 1P9D 1QZE 1TP4 1ZO6 2WYQ 5XBO
Enriched GO Terms of Interacting Partners?
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