MPG and GPR182

Data Source:
BioGRID (two hybrid)

		MPG	GPR182
Description		N-methylpurine DNA glycosylase	G protein-coupled receptor 182
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Mitochondrial Nucleoid	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Damaged DNA Binding Alkylbase DNA N-glycosylase Activity Protein Binding DNA-3-methyladenine Glycosylase Activity DNA N-glycosylase Activity DNA-7-methylguanine Glycosylase Activity DNA-7-methyladenine Glycosylase Activity DNA-3-methylguanine Glycosylase Activity	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity
	Biological Process	Base-excision Repair DNA Dealkylation Involved In DNA Repair Depurination	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway
Pathways		Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Displacement of DNA glycosylase by APEX1
Drugs		Cisplatin Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576) Glioblastoma ( 28346443) Hemoglobin levels ( 26366553) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell traits ( 23446634)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Heel bone mineral density ( 28869591) Refractive error ( 32231278)
Interacting Genes		13 interacting genes: APP CRK EP300 ESR1 FBXO7 GPR182 HSD17B14 MLH1 RAD23A RAD23B RXRA TERF2IP THRB	10 interacting genes: ABHD12 GOSR1 HLA-C ITGA5 MPG OGFR PLPPR3 TMEM101 TMEM30A TMUB2
Entrez ID		4350	11318
HPRD ID		06766	05605
Ensembl ID		ENSG00000103152	ENSG00000166856
Uniprot IDs		P29372 Q1W6H1	O15218
PDB IDs		1BNK 1EWN 1F4R 1F6O 3QI5 3UBY
Enriched GO Terms of Interacting Partners?
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