ASL and TRIM3

		ASL	TRIM3
Description		argininosuccinate lyase	tripartite motif containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Cytoplasm Early Endosome Golgi Apparatus Dendrite
	Molecular Function	Argininosuccinate Lyase Activity Protein Binding Identical Protein Binding	Protein Binding Protein C-terminus Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Urea Cycle Arginine Biosynthetic Process Via Ornithine	Protein Polyubiquitination Nervous System Development Protein Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Urea cycle	Interferon gamma signaling
Drugs		Arginine Argininosuccinate 2-(N-morpholino)ethanesulfonic acid
Diseases		Argininosuccinic aciduria (ARGINSA); Argininosuccinate lyase deficiency
GWAS			Malaria ( 31844061)
Interacting Genes		10 interacting genes: CLK1 CSNK2A2 FBP1 HMOX1 MCMBP NTAQ1 OVGP1 QARS1 SRPK2 TRIM3	30 interacting genes: ACTN4 ASL CDKN1A CEP70 CSNK1D CSNK1E KCTD7 KIF21B LNX1 LRRC8E MYO5A MYO5B ROPN1 TEAD1 TEAD2 TNFAIP3 TPTEP2-CSNK1E TRIM2 TRIM21 UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2G2 UBE2I UBE2K UBE2U UBE2Z USP32
Entrez ID		435	10612
HPRD ID		01948	05690
Ensembl ID		ENSG00000126522	ENSG00000110171
Uniprot IDs		A0A024RDL8 A0A0S2Z316 P04424	B7Z5Y8 O75382
PDB IDs		1AOS 1K62
Enriched GO Terms of Interacting Partners?
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