TRIM3 and ROPN1

Data Source:
BioGRID (two hybrid)

		TRIM3	ROPN1
Description		tripartite motif containing 3	rhophilin associated tail protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Early Endosome Golgi Apparatus Dendrite	Nucleus Cytoplasm Motile Cilium
	Molecular Function	Protein Binding Protein C-terminus Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding Identical Protein Binding
	Biological Process	Protein Polyubiquitination Nervous System Development Protein Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Regulation Of Protein Phosphorylation Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium
Pathways		Interferon gamma signaling	RHO GTPases Activate Rhotekin and Rhophilins
Drugs
Diseases
GWAS		Malaria ( 31844061)	Benign childhood epilepsy with centro-temporal spikes ( 32580138) Household income ( 31844048) Household income (MTAG) ( 31844048)
Interacting Genes		30 interacting genes: ACTN4 ASL CDKN1A CEP70 CSNK1D CSNK1E KCTD7 KIF21B LNX1 LRRC8E MYO5A MYO5B ROPN1 TEAD1 TEAD2 TNFAIP3 TPTEP2-CSNK1E TRIM2 TRIM21 UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2G2 UBE2I UBE2K UBE2U UBE2Z USP32	50 interacting genes: AKAIN1 AKAP14 AKAP3 AKAP5 AKAP7 AP1M1 BTBD16 CDC37 CEP57L1 CKS1B CNST DBF4B ERCC3 FAM110A FAM153A FAM153B FAM161A FAM90A1 GNL3L GPKOW HNRNPUL1 KIAA0753 KIF9 LENG1 LMO4 LNX1 LNX2 NTAQ1 PICK1 PKP2 POLR3C PRDM6 PRKAA1 PSMA1 RHPN1 RTP5 SDCBP SERTAD1 SORBS3 SPA17 SPG21 SYTL4 TRIM3 TSGA10IP TSHZ3 TSNAXIP1 TULP3 UBE2W VPS33A XKR3
Entrez ID		10612	54763
HPRD ID		05690	15269
Ensembl ID		ENSG00000110171	ENSG00000065371
Uniprot IDs		B7Z5Y8 O75382	A0A140VKB2 Q9HAT0
PDB IDs
Enriched GO Terms of Interacting Partners?
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