MOCS2 and MOCS3

Data Source:
HPRD (in vivo)

		MOCS2	MOCS3
Description		molybdenum cofactor synthesis 2	molybdenum cofactor synthesis 3
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol Nuclear Speck Molybdopterin Synthase Complex	Cytoplasm Cytosol
	Molecular Function	Molybdopterin Synthase Activity	Thiosulfate Sulfurtransferase Activity Protein Binding ATP Binding Nucleotidyltransferase Activity Sulfurtransferase Activity URM1 Activating Enzyme Activity Metal Ion Binding Molybdopterin-synthase Sulfurtransferase Activity Molybdopterin-synthase Adenylyltransferase Activity
	Biological Process	Mo-molybdopterin Cofactor Biosynthetic Process Molybdopterin Cofactor Biosynthetic Process	TRNA Wobble Uridine Modification TRNA Wobble Position Uridine Thiolation Mo-molybdopterin Cofactor Biosynthetic Process Protein Phosphopantetheinylation Molybdopterin Cofactor Biosynthetic Process Protein Urmylation TRNA Thio-modification
Pathways		Molybdenum cofactor biosynthesis Molybdenum cofactor biosynthesis	Molybdenum cofactor biosynthesis
Drugs
Diseases		Xanthinuria
GWAS		Acne (severe) ( 24927181) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Intraocular pressure ( 29235454) Systemic juvenile idiopathic arthritis ( 27927641)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756)
Interacting Genes		5 interacting genes: ABCF3 KRAS MOCS3 RPL9 STK11	3 interacting genes: EXOSC6 MOCS2 XRN2
Entrez ID		4338	27304
HPRD ID		04750	10092
Ensembl ID		ENSG00000164172	ENSG00000124217
Uniprot IDs		A0A024QZS1 O96007 O96033	O95396
PDB IDs		4AP8 5MPO	3I2V
Enriched GO Terms of Interacting Partners?
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