ASGR1 and KIR2DL3

Data Source:
BioGRID (two hybrid)

		ASGR1	KIR2DL3
Description		asialoglycoprotein receptor 1	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Metal Ion Binding	Antigen Binding Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process	Receptor-mediated Endocytosis Viral Process Protein N-linked Glycosylation Via Asparagine Cellular Response To Extracellular Stimulus	Immune Response Regulation Of Immune Response
Pathways		Asparagine N-linked glycosylation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 22001757) Low density lipoprotein cholesterol levels ( 32154731) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 31666285 29403010)
Interacting Genes		43 interacting genes: AHNAK2 AMIGO1 APH1A APP ASGR2 ATP1B4 BLCAP CERS2 CLDN7 CLEC4G CPLX4 CREB3L1 CYB5R3 DHFR ERGIC3 FAM209A FCGR1A FNDC9 GPX8 HIBADH HIVEP1 HSP90AA1 HSP90B1 IGFBP5 KIR2DL3 LAMTOR5 LEUTX LMNA MCEMP1 NEMP1 NLK PDZK1IP1 RBBP6 RNF19B SAR1A SLC10A1 SLC35C2 SPAG4 SUSD3 TG TMX2 VKORC1 VSIR	64 interacting genes: ADGRE2 AGTRAP AIG1 ANKRD46 APOA2 APOD APP AQP10 ASGR1 ATP6V0E1 BMP10 BRICD5 BTN2A2 C3orf52 CDIPT CISD2 CLDN19 CLN6 COQ9 CXCL16 CXCL9 CYB5B CYBC1 EMD FAM209A FAM3C FUNDC2 GAST GJA8 GPR108 GPX8 HLA-C IFITM3 INSIG2 ITGAM JAGN1 KTN1 LAT LCK LEUTX LHFPL5 NINJ2 NRM NSG1 OLFM4 PLN PLPPR2 PTPN6 RNF152 RTP2 SEC22B SLC38A7 SMIM1 SNORC THBD TMEM218 TMEM222 TMEM243 TMEM86B TMEM97 TRAF3IP3 UPK1B UPK2 VAMP5
Entrez ID		432	3804
HPRD ID		00151	10383
Ensembl ID		ENSG00000141505	ENSG00000243772
Uniprot IDs		P07306 Q6FGQ5	E3NZD8 P43628
PDB IDs		1DV8 5JPV 5JQ1	1B6U
Enriched GO Terms of Interacting Partners?
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