ASGR1 and ATP1B4

Data Source:
BioGRID (two hybrid)

		ASGR1	ATP1B4
Description		asialoglycoprotein receptor 1	ATPase Na+/K+ transporting family member beta 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane	Nuclear Envelope Nuclear Inner Membrane Integral Component Of Plasma Membrane Sodium:potassium-exchanging ATPase Complex
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Metal Ion Binding	Protein Binding Inorganic Cation Transmembrane Transporter Activity
	Biological Process	Receptor-mediated Endocytosis Viral Process Protein N-linked Glycosylation Via Asparagine Cellular Response To Extracellular Stimulus	Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Inorganic Cation Transmembrane Transport
Pathways		Asparagine N-linked glycosylation	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 22001757) Low density lipoprotein cholesterol levels ( 32154731) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 31666285 29403010)	Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		43 interacting genes: AHNAK2 AMIGO1 APH1A APP ASGR2 ATP1B4 BLCAP CERS2 CLDN7 CLEC4G CPLX4 CREB3L1 CYB5R3 DHFR ERGIC3 FAM209A FCGR1A FNDC9 GPX8 HIBADH HIVEP1 HSP90AA1 HSP90B1 IGFBP5 KIR2DL3 LAMTOR5 LEUTX LMNA MCEMP1 NEMP1 NLK PDZK1IP1 RBBP6 RNF19B SAR1A SLC10A1 SLC35C2 SPAG4 SUSD3 TG TMX2 VKORC1 VSIR	7 interacting genes: ASGR1 C3orf52 CSGALNACT2 CXCL9 ERMP1 SMIM3 TSPAN2
Entrez ID		432	23439
HPRD ID		00151	06453
Ensembl ID		ENSG00000141505	ENSG00000101892
Uniprot IDs		P07306 Q6FGQ5	Q9UN42
PDB IDs		1DV8 5JPV 5JQ1
Enriched GO Terms of Interacting Partners?
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