DNAJB9 and FSCN1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DNAJB9	FSCN1
Description		DnaJ heat shock protein family (Hsp40) member B9	fascin actin-bundling protein 1
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GO Annotations	Cellular Component	Nucleolus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Extracellular Exosome	Stress Fiber Ruffle Podosome Cytoplasm Cytosol Cytoskeleton Microvillus Cell-cell Junction Cell Cortex Actin Cytoskeleton Lamellipodium Filopodium Growth Cone Cell Projection Membrane Microspike Extracellular Exosome
	Molecular Function	Protein Binding Hsp70 Protein Binding Chaperone Binding Misfolded Protein Binding	RNA Binding Actin Binding Protein Binding Drug Binding Protein-macromolecule Adaptor Activity Cadherin Binding Actin Filament Binding
	Biological Process	Immunoglobulin Production B Cell Differentiation Ubiquitin-dependent ERAD Pathway Response To Endoplasmic Reticulum Stress IRE1-mediated Unfolded Protein Response Negative Regulation Of IRE1-mediated Unfolded Protein Response	Cell-cell Junction Assembly Establishment Or Maintenance Of Cell Polarity Positive Regulation Of Lamellipodium Assembly Cell Migration Cytokine-mediated Signaling Pathway Microspike Assembly Actin Cytoskeleton Organization Parallel Actin Filament Bundle Assembly Regulation Of Microvillus Assembly Regulation Of Actin Cytoskeleton Organization Establishment Of Apical/basal Cell Polarity Cell Motility Actin Filament Bundle Assembly Positive Regulation Of Filopodium Assembly Positive Regulation Of Podosome Assembly Positive Regulation Of Extracellular Matrix Disassembly
Pathways		XBP1(S) activates chaperone genes	Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Metabolite levels ( 23823483) Smoking behavior ( 22006218)
Interacting Genes		10 interacting genes: DYNLL1 ECPAS FAM71C FSCN1 MYL6 PLK1 RFK SLC16A8 TCEA2 TCERG1	12 interacting genes: ACTA1 ACTC1 CTNNB1 DNAJB9 MAPK8IP2 NGFR OXTR PRKCA PRKCD RAB1A SMURF1 YWHAQ
Entrez ID		4189	6624
HPRD ID		07047	04068
Ensembl ID		ENSG00000128590	ENSG00000075618
Uniprot IDs		Q6FIF1 Q9UBS3	A0A384MEG1 B3KTA3 Q16658
PDB IDs		2CTR	1DFC 3LLP 3P53 4GOV 4GOY 4GP0 4GP3 6B0T 6I0Z 6I10 6I11 6I12 6I13 6I14 6I15 6I16 6I17 6I18
Enriched GO Terms of Interacting Partners?
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