MIR200C and LRPPRC

Data Source:
BioGRID (unspecified method)

		MIR200C	LRPPRC
Description		microRNA 200c	leucine rich pentatricopeptide repeat containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Condensed Nuclear Chromosome Nucleus Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Mitochondrion Cytoskeleton Microtubule Membrane Mitochondrial Nucleoid Perinuclear Region Of Cytoplasm Ribonucleoprotein Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	Single-stranded DNA Binding RNA Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Cytokine Production Positive Regulation Of Neuron Projection Development Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Interleukin-33 Production Negative Regulation Of Neuron Death Response To Amyloid-beta Regulation Of Vascular Endothelial Cell Proliferation Positive Regulation Of Mesodermal Cell Differentiation	Negative Regulation Of Mitochondrial RNA Catabolic Process Mitochondrion Transport Along Microtubule MRNA Transport Regulation Of Mitochondrial Translation
Pathways			TP53 Regulates Metabolic Genes Respiratory electron transport
Drugs
Diseases
GWAS			Alcohol consumption (drinks per week) ( 30679032) Bitter alcoholic beverage consumption ( 31046077) Chronotype ( 30696823) Hand grip strength ( 29691431 29313844) Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355) Medication use (calcium channel blockers) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Morning person ( 30696823) Refractive error ( 32231278) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		89 interacting genes: AIMP2 AQR ATXN2L C1QBP CHERP CPSF1 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 ELAC1 EPRS1 ESRP1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUFIP2 PDCD11 PTBP1 PTBP3 PTCD3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCB SART3 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM56 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	82 interacting genes: ANKRD1 CECR2 FOXO1 HEBP2 LINC01554 MAP1S MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NFKBIB PPARGC1A PTEN UXT
Entrez ID		406985	10128
HPRD ID			06343
Ensembl ID		ENSG00000207713	ENSG00000138095
Uniprot IDs			E5KNY5 P42704
PDB IDs
Enriched GO Terms of Interacting Partners?
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