CPSF2 and MIRLET7A3

Data Source:
BioGRID (unspecified method)

		CPSF2	MIRLET7A3
Description		cleavage and polyadenylation specific factor 2	microRNA let-7a-3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Membrane
	Molecular Function	RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA 3'-end Processing By Stem-loop Binding And Cleavage MRNA Export From Nucleus MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation	Gene Silencing By MiRNA
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		3-month functional outcome in lacunar ischaemic stroke (modified Rankin score) ( 30796134) B cell acute lymphoblastic leukaemia (hyperdiploid negative) ( 29296818) B cell acute lymphoblastic leukaemia (normal cytogenetics) ( 29296818) B cell acute lymphoblastic leukaemia (Philadelphia chromosome negative) ( 29296818) Dialysis-related mortality ( 21546767) Height ( 18391951) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Monobrow ( 27182965) Myopia ( 27182965) Obesity-related traits ( 23251661) Refractive error ( 32231278)
Interacting Genes		10 interacting genes: MIR19A MIR19B1 MIR92A1 MIR92A2 MIRLET7A1 MIRLET7A3 MIRLET7F2 POLR2A SUMO2 WWOX	100 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CELF1 CPSF1 CPSF2 CSTF1 CSTF3 DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PRMT1 PTBP1 PUM1 PUM2 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM12B RBM14 RBM4 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM25 TRMT10C U2SURP UPF1 UTP20 YBX1 YBX3 ZFR ZNF346
Entrez ID		53981	406883
HPRD ID		05824
Ensembl ID		ENSG00000165934	ENSG00000283990
Uniprot IDs		A0A024R6H0 Q9P2I0
PDB IDs		6URG 6V4X
Enriched GO Terms of Interacting Partners?
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