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MIR15B and CPSF1
Data Source:
BioGRID
(unspecified method)
MIR15B
CPSF1
Description
microRNA 15b
cleavage and polyadenylation specific factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Extracellular Vesicle
Nucleus
Nucleoplasm
MRNA Cleavage And Polyadenylation Specificity Factor Complex
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Protein Binding
Enzyme Binding
MRNA 3'-UTR AU-rich Region Binding
Biological Process
Branching Involved In Blood Vessel Morphogenesis
Cardiac Muscle Hypertrophy
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Angiogenesis
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Apoptotic Process
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Neuron Apoptotic Process
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Translation
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Inflammatory Response
Negative Regulation Of Wound Healing
Negative Regulation Of Trophoblast Cell Migration
Negative Regulation Of NIK/NF-kappaB Signaling
Negative Regulation Of Amyloid-beta Formation
Negative Regulation Of Amyloid Precursor Protein Catabolic Process
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Positive Regulation Of Connective Tissue Replacement
Negative Regulation Of Vascular Endothelial Cell Proliferation
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
MRNA Splicing, Via Spliceosome
Termination Of RNA Polymerase II Transcription
MRNA Polyadenylation
TRNA Splicing, Via Endonucleolytic Cleavage And Ligation
MRNA Export From Nucleus
MRNA 3'-end Processing
Pre-mRNA Cleavage Required For Polyadenylation
Pathways
Transport of Mature mRNA Derived from an Intronless Transcript
tRNA processing in the nucleus
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Bipolar disorder (
31043756
)
Malaria (
31844061
)
Educational attainment (
25201988
)
Interacting Genes
102 interacting genes:
ADARB1
AIMP1
APOBEC3B
AQR
ATXN2L
C1QBP
CELF1
CPSF1
CSTF3
DARS1
DCP1A
DCP1B
DCP2
DDX1
DDX21
DDX3X
DDX3Y
DHX36
DHX37
EDC3
EDC4
EIF2AK2
EPRS1
ERAL1
ESRP1
FAM98A
FIP1L1
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LRPPRC
MARS1
MATR3
MSI1
MSI2
NOL6
NONO
NUDT21
NUFIP2
PATL1
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RBM45
RBMS2
RTCA
RTCB
SF3A1
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TENT2
TRA2A
TRA2B
U2SURP
UPF1
USP36
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
57 interacting genes:
CSTF2T
GLIS2
HMOX1
IL7R
INCA1
MCM2
MIR1-2
MIR106B
MIR107
MIR122
MIR128-2
MIR138-1
MIR138-2
MIR143
MIR155
MIR15A
MIR15B
MIR16-2
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200C
MIR205
MIR206
MIR20B
MIR21
MIR214
MIR221
MIR29A
MIR31
MIR34A
MIR34B
MIR7-1
MIR92A1
MIR92A2
MIR98
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7E
MIRLET7F2
MIRLET7G
MIRLET7I
NEDD4
PAPOLA
POLR2A
PRRC2A
REL
TAF11
TAF12
TAF13
TAF5
TAF7
Entrez ID
406949
29894
HPRD ID
05823
Ensembl ID
ENSG00000207779
ENSG00000071894
Uniprot IDs
Q10570
PDB IDs
6BLY
6BM0
6DNH
6F9N
6FBS
6FUW
6URG
6URO
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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