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MIR141 and DHX36
Data Source:
BioGRID
(unspecified method)
MIR141
DHX36
Description
microRNA 141
DEAH-box helicase 36
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Chromosome, Telomeric Region
Intracellular Anatomical Structure
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Cytoplasmic Stress Granule
Nuclear Speck
Axon
Dendrite
Perikaryon
Extracellular Exosome
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Magnesium Ion Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
G-quadruplex RNA Binding
DNA Helicase Activity
Single-stranded DNA Binding
RNA Binding
RNA Helicase Activity
Double-stranded RNA Binding
MRNA 3'-UTR Binding
Protein Binding
ATP Binding
DNA-dependent ATPase Activity
MRNA 3'-UTR AU-rich Region Binding
Histone Deacetylase Binding
MRNA 5'-UTR Binding
G-quadruplex DNA Binding
Telomerase RNA Binding
Pre-miRNA Binding
Biological Process
Positive Regulation Of Cell Population Proliferation
Gene Silencing By MiRNA
Negative Regulation Of Viral Genome Replication
Negative Regulation Of Inflammatory Response
Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Ossification
Positive Regulation Of Myeloid Dendritic Cell Cytokine Production
Regulation Of Transcription By RNA Polymerase III
Spermatogenesis
RNA Secondary Structure Unwinding
Positive Regulation Of Gene Expression
Negative Regulation Of Translation
Positive Regulation Of MRNA 3'-end Processing
Positive Regulation Of Telomere Maintenance
Positive Regulation Of Type I Interferon Production
DNA Duplex Unwinding
Positive Regulation Of Interferon-alpha Production
Cellular Response To Heat
Cellular Response To UV
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Exogenous DsRNA
Regulation Of MRNA Stability
G-quadruplex DNA Unwinding
Innate Immune Response
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Embryonic Development
Defense Response To Virus
Positive Regulation Of Cardioblast Differentiation
Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Dendritic Spine Morphogenesis
3'-UTR-mediated MRNA Destabilization
Telomerase RNA Stabilization
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Positive Regulation Of Hematopoietic Progenitor Cell Differentiation
Regulation Of Transcription From RNA Polymerase II Promoter Involved In Spermatogenesis
Cellular Response To Arsenite Ion
Positive Regulation Of Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Intracellular MRNA Localization
Positive Regulation Of Cytoplasmic Translation
Pathways
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
Drugs
Diseases
GWAS
Blood protein levels (
29875488
)
Body mass index (
29273807
)
Response to cognitive-behavioural therapy in anxiety disorder (
31123309
)
Interacting Genes
87 interacting genes:
ADARB1
APOBEC3B
C1QBP
CPSF7
DARS1
DDX1
DDX21
DDX23
DDX3X
DHX36
EDC4
EIF2AK2
EPRS1
ERAL1
ESRP1
FAM98A
FAM98B
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP6
LARP7
LIN28A
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NONO
NUDT16L1
NUDT21
P3H1
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
QARS1
QKI
RARS1
RBFOX2
RBM14
RBM4
RTCA
RTCB
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYNCRIP
TAF15
TENT2
TRA2B
TRMT1L
UPF1
UTP20
YBX1
YBX2
YBX3
ZC3H11A
ZNF346
71 interacting genes:
DUX4
IL7R
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F2
MIRLET7G
MIRLET7I
TLR1
ZFP36
Entrez ID
406933
170506
HPRD ID
09918
Ensembl ID
ENSG00000207708
ENSG00000174953
Uniprot IDs
Q9H2U1
PDB IDs
2N16
2N21
6Q6R
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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