MIRLET7A1 and TUT7

Data Source:
BioGRID (unspecified method)

		MIRLET7A1	TUT7
Description		microRNA let-7a-1	terminal uridylyl transferase 7
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Exosome Extracellular Vesicle	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding Protein Binding Zinc Ion Binding Nucleotidyltransferase Activity MiRNA Binding RNA Uridylyltransferase Activity Uridylyltransferase Activity
	Biological Process	Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Interleukin-6-mediated Signaling Pathway Deadenylation Involved In Gene Silencing By MiRNA	Nuclear-transcribed MRNA Poly(A) Tail Shortening Oocyte Maturation Negative Regulation Of Transposition, RNA-mediated MiRNA Metabolic Process Pre-miRNA Processing RNA 3'-end Processing Histone MRNA Catabolic Process RNA 3' Uridylation Polyuridylation-dependent MRNA Catabolic Process
Pathways			Deadenylation of mRNA
Drugs
Diseases
GWAS
Interacting Genes		101 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CPSF2 CPSF6 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC LSM10 LSM11 MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM4 RTCB SAFB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM25 TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	14 interacting genes: APP MIR138-2 MIR25 MIRLET7A1 MIRLET7A2 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I ZDHHC17
Entrez ID		406881	79670
HPRD ID			11697
Ensembl ID		ENSG00000199165	ENSG00000083223
Uniprot IDs			Q5VYS8 Q96KX5 X6R3Q3
PDB IDs			5W0B 5W0M 5W0N 5W0O
Enriched GO Terms of Interacting Partners?
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