MIRLET7A1 and EDC4

Data Source:
BioGRID (unspecified method)

		MIRLET7A1	EDC4
Description		microRNA let-7a-1	enhancer of mRNA decapping 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Exosome Extracellular Vesicle	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	Protein Binding
	Biological Process	Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Interleukin-6-mediated Signaling Pathway Deadenylation Involved In Gene Silencing By MiRNA	Biological_process Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Exonucleolytic Catabolism Of Deadenylated MRNA
Pathways			mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS			HDL cholesterol ( 21347282) Metabolic syndrome ( 22399527) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		101 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CPSF2 CPSF6 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC LSM10 LSM11 MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM4 RTCB SAFB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM25 TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	38 interacting genes: CCL5 CDC42 EIF2AK2 FBLN1 GIT2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR122 MIR128-2 MIR141 MIR15B MIR199A1 MIR200A MIR200B MIR200C MIR205 MIR20A MIR21 MIR214 MIR222 MIR29C MIR34A MIR34C MIR363 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7C MIRLET7D MIRLET7E SUMO2 YTHDC1
Entrez ID		406881	23644
HPRD ID			06911
Ensembl ID		ENSG00000199165	ENSG00000038358
Uniprot IDs			Q6P2E9
PDB IDs
Enriched GO Terms of Interacting Partners?
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