BCAM and TRIM7

Data Source:
BioGRID (two hybrid)

		BCAM	TRIM7
Description		basal cell adhesion molecule (Lutheran blood group)	tripartite motif containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome	Nucleus Cytoplasm Golgi Apparatus
	Molecular Function	Transmembrane Signaling Receptor Activity Laminin Receptor Activity Protein Binding Protein C-terminus Binding Laminin Binding	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cell Adhesion Cell-matrix Adhesion Signal Transduction	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease ( 30636644 24755620) Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease in hypertension ( 31055733) Alzheimer's disease in hypertension-negative individuals ( 31055733) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Carotid intima media thickness (maximum) ( 31801372) Carotid intima media thickness (mean) ( 31801372) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Cerebrospinal fluid AB1-42 levels ( 28247064 29274321) Cerebrospinal fluid p-tau levels ( 29274321) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid t-tau levels ( 29274321) Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321) Hippocampal volume ( 29274321) Hippocampal volume in Alzheimer's disease dementia ( 29274321) LDL cholesterol ( 30275531) Logical memory (delayed recall) ( 29274321) Logical memory (immediate recall) ( 29274321) Waist-to-hip circumference ratio (smoking years interaction) ( 23192594)
Interacting Genes		10 interacting genes: EPB41 KLHL2 KRTAP1-1 KRTAP1-3 LAMA5 MDFI NBPF19 NOTCH2NLA TRIM7 UBE2I	27 interacting genes: AQP1 BCAM CDK13 CFL2 CRYGC CTNNAL1 DES GTF2A2 GYG1 IRAK4 MAD2L2 NAA35 NABP1 OTUD6A RAB2A RIN1 RNASE1 RSPH14 RWDD2B SIAH1 SRC TP53I13 TRMT10A UBE2D1 UBE2D2 UBE2D3 UBE2E1
Entrez ID		4059	81786
HPRD ID		00197	11648
Ensembl ID		ENSG00000187244	ENSG00000146054
Uniprot IDs		A0A087WXM8 P50895	Q9C029
PDB IDs		2PET 2PF6
Enriched GO Terms of Interacting Partners?
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