TRIM7 and CDK13

Data Source:
BioGRID (two hybrid)

		TRIM7	CDK13
Description		tripartite motif containing 7	cyclin dependent kinase 13
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus	Cyclin-dependent Protein Kinase Holoenzyme Complex Cyclin K-CDK13 Complex Extracellular Region Extracellular Space Nucleus Nucleoplasm Golgi Apparatus Cytosol Cyclin/CDK Positive Transcription Elongation Factor Complex Nuclear Speck Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	RNA Binding Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity Protein Kinase Binding Cyclin Binding
	Biological Process	Protein Ubiquitination	Alternative MRNA Splicing, Via Spliceosome Transcription Elongation From RNA Polymerase II Promoter Protein Phosphorylation Regulation Of Mitotic Nuclear Division Multicellular Organism Development Positive Regulation Of Cell Population Proliferation Viral Process Hemopoiesis Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Neutrophil Degranulation Phosphorylation Of RNA Polymerase II C-terminal Domain Negative Regulation Of Stem Cell Differentiation
Pathways			TP53 Regulates Transcription of DNA Repair Genes Neutrophil degranulation
Drugs
Diseases
GWAS			Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Plateletcrit ( 32888494) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		27 interacting genes: AQP1 BCAM CDK13 CFL2 CRYGC CTNNAL1 DES GTF2A2 GYG1 IRAK4 MAD2L2 NAA35 NABP1 OTUD6A RAB2A RIN1 RNASE1 RSPH14 RWDD2B SIAH1 SRC TP53I13 TRMT10A UBE2D1 UBE2D2 UBE2D3 UBE2E1	4 interacting genes: CHMP4A PRPF40A SRPK2 TRIM7
Entrez ID		81786	8621
HPRD ID		11648	04496
Ensembl ID		ENSG00000146054	ENSG00000065883
Uniprot IDs		Q9C029	A0A024RA66 A0A024RA85 Q14004 Q9BVE2
PDB IDs			5EFQ
Enriched GO Terms of Interacting Partners?
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