LSP1 and IL24

Data Source:
BioGRID (two hybrid)

		LSP1	IL24
Description		lymphocyte specific protein 1	interleukin 24
Image
GO Annotations	Cellular Component	Plasma Membrane Actin Cytoskeleton Membrane Extracellular Exosome	Extracellular Region Extracellular Space
	Molecular Function	Actin Binding	Cytokine Activity Protein Binding
	Biological Process	Cellular Defense Response Signal Transduction	Apoptotic Process Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Negative Regulation Of Cell Migration Wound Healing Serine Phosphorylation Of STAT Protein Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Cellular Response To Lipopolysaccharide Cellular Response To Interleukin-4
Pathways			Interleukin-20 family signaling
Drugs
Diseases
GWAS		Bladder cancer ( 24163127) Breast cancer ( 29059683 17529967 23535729 27117709 20453838) Breast cancer (estrogen-receptor negative) ( 27117709) Celiac disease ( 23936387) Central corneal thickness ( 32528159) Diastolic blood pressure ( 27841878 27618452 30487518) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Granulocyte percentage of myeloid white cells ( 27863252) Hypertension ( 30487518) Inflammatory bowel disease ( 28067908 23128233) Lymphocyte counts ( 32888494) Mammographic density (dense area) ( 25342443) Mean arterial pressure ( 29403010 30487518) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (antihypertensives) ( 31015401) Medication use (beta blocking agents) ( 31015401) Methadone dose in opioid dependence ( 28115739) Milk allergy ( 25710614) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Potassium levels ( 29403010) Pulse pressure ( 27841878 30578418) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure ( 27841878 29403010 27618452 30487518 30578418) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Ulcerative colitis ( 28067908 21297633)	Inflammatory bowel disease ( 23128233)
Interacting Genes		10 interacting genes: ACTG1 BMPR2 GREB1 IL24 KLK6 LYPD3 MAPKAPK2 SCGB2A2 SNAI1 THRSP	25 interacting genes: AKT1 APC ATM BAG4 CASP8 CCR5 CLU DCD ESR2 FBXW7 HMMR HRAS IL20RA KRAS LSP1 NOTCH2 PALB2 PARP1 PIK3CA PTEN RAD51 RARG RB1CC1 RIPK3 SMAD4
Entrez ID		4046	11009
HPRD ID		01083	04995
Ensembl ID		ENSG00000130592	ENSG00000162892
Uniprot IDs		A8K7L8 P33241	Q13007
PDB IDs		3BH8 4NO0 4NO2	6DF3 6GG1
Enriched GO Terms of Interacting Partners?
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